• ASBMB 2016 Annual Meeting

Metabolism, Disease and Drug Design

Oral presentations selected from volunteered abstracts will also be programmed for a poster presentation. Programming notifications will be sent in January.  We look forward to seeing you at the 2016 ASBMB Annual Meeting, April 2 - 6, 2016, San Diego, Calif.

Theme Organizers
: Clifton Barry, NIH/NIAID and John Kozarich, Activx Biosciences 

Sunday, April 3, 2016
San Diego Convention Center, Room 6E
4:00 pm - 6:15 pm
Omics Approaches to Target Discovery 
Session Chair: Jason Sello, Brown Univ.

Metabolomic Signatures of Drug Mechanism of Action
Kyu Rhee, Weill Cornell Medical College
Toward a Functional, ChemoProteomic Interrogation of Kinome and Nucleotide Binding Space
John Kozarich, Activx Biosciences
Lipidomics in Disease and Drug Discovery
Edward DennisIUniv. of California, San Diego


Monday, April 4, 2016
San Diego Convention Center, Room 6E
9:45 am - 12:00 pm
Mechanistically-Informed Drug Design 
Session Chair: John Kozarich, Activx Biosciences

Trans-translation as a Target for Novel Antibiotics
Kenneth Keiler, Penn State Univ.
Targeting CoA biosynthesis in M. tuberculosis
Valerie Mizrahi, Univ. of Cape Town
Rational Optimization of Natural-Born, Mechanism-Based Inhibitors of the 20S Proteasomes in Humans and Mycobacterium Tuberculosis
Jason Sello, Brown Univ.


Tuesday, April 5, 2016
San Diego Convention Center, Room 6E
4:00 pm - 6:15 pm
Natural Product Biosynthesis for New Drug Leads 
Session Chair: Clifton Barry, NIH/NIAID

Culture Independent Approaches for the Discovery of New Bacterial Metabolites
Sean Brady, Rockefeller Univ.
Semisynthetic Natural Products
Richard Lee, St. Jude's Children's Hosp.
Nature Bank
Ron Quinn, Griffith Univ., Australia


Wednesday, April 6, 2016
San Diego Convention Center, Room 6E
9:45 am - 12:00 pm
Biochemically-Informed Imaging in Drug Discovery 
Session Chair: TBD

Exploiting Trehalose Biology in the Development of Novel PET Imaging Agents for TB
Clifton BarryNIH/NIAID 
Imaging Mass Spectrometry - the Pyrazinamide Enigma
Veronique DertoisRutgers Univ.
Fluorogenic Probes for Esterase and Lipase Detection
Kimberly Beatty, Oregon Health and Sciences Univ.