Program

Sunday, Apr. 7

 
 
Advances in Cryo EM    
Cryo-EM Analysis of Full-length Receptor Tyrosine Kinase
Xiaochen Bai, University of Texas Southwestern Medical Center
Getting Better Images Easier for Single Particle Cryo-EM
Anchi Cheng, New York Structural Biology Center

Title Tba.
Elizabeth Hua-Mei Kellogg, Cornell University
Single Particle Cryo-EM Studies of Membrane Proteins  
Yifan Cheng,  University of California, San Francisco, Session Organizer and Chair
 
 
Autophagy and Proteostasis    
Endoplasmic reticulum turnover via selective autophagy
Ivan Dikic, University of Goethe
Regulation of Mitophagy by Lipid Binding Proteins
Anne Simonsen, Institute of Basic Medical Sciences, University of Oslo
The Biochemical Program of Extreme Terminal Differentiation
Daniel Finley, Harvard Medical School
New Links Between the Autophagy Machinery and Cellular Homeostasis 
Beth Levine, University of Texas Southwestern Medical Center, Session Organizer and Chair
 
 
 
Catalysis and Enzyme Action    
 
Covalent Intermediates in Flavoenzyme Catalysis 
Pablo Sobrado, Virginia Polytechnic Institute and State University, Session Organizer and Chair
Homologous Trans-editing Factors with Broad Substrate Specificity Prevent Global Mistranslation 
Karin Musier-Forsyth, Ohio State University
Discovering Novel Enzymes and Novel Metabolic Pathways 
John A. Gerlt, University of Illinois, Urbana-Champaign
Structural Insight into Pre-mRNA Splicing Catalyzed by the Spliceosome
Rui Zhao, University of Colorado, Denver Anschutz Medical Campus
 
 
Epigenomics and Chromatin Dynamics    
Title tba.
Maya Capelson, University of Pennsylvania, Perelman School of Medicine
Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer
Cigall Kadoch, Dana Farber Cancer Institute
Regulation of Chromatin Organization at Enhancers
Bing Ren, University of California-San Diego/ Ludwig Institute for Cancer Research
Chromatin Regulation of Tumor Responses to Immune Checkpoint Blockade
Yang Shi, Boston Children's Hospital, Session Organizer and Chair
 
 
Microbiome and Disease    
Personalizing Food to the Gut Microbiome
Lawrence David, Duke University
Bacterial modification of bile acids alters host physiology
Sloan Devlin, Harvard Medical School
Connecting Variation in the Gut Microbiome with Development of Vascular Disease
Federico E. Rey, University of Wisconsin-Madison
Human Skin Microbiome: Integrating Bacterial, Fungal and Viral Communities
Julie Segre, National Human Genome Research Institute, Session Organizer and Chair
 
 
Mitochondria Dysfunction & Disease, organized by SEBM    
Session detail tba. 
 
 
Synthetic Biology    
Synthetic Biology Approaches To New Chemistry
Michelle Chang, University of California, Berkeley, Session Organizer and Chair
Development of a Targeted Diversifier Allowing Mutation of All Nucleotide Types In Vivo
John Dueber, University of California, Berkeley
Base Editing: Chemistry on a Target Nucleotide in the Genome of Living Cells
David R. Liu, Broad Institute, Harvard University, HHMI
Biosynthesis of Complex Plant-Derived Natural Products
Christina Smolke, Stanford University, Schools of Engineering and Medicine
 
 
Novel Cancer Therapies: Free Radical Biology, organized by SEBM    
Doug Spitts and Rick Domann, Session Organizers and Co-chairs
Session detail tba 
 
 
Using Large Sets of Data with Students, organized by the ASBMB Education and Professional Development Committee    
Big Data Analysis and Visualization with Undergraduates: Training, Competency-Based Assessment and Meaningful Research Outcomes
Ian Page, University of Maryland, College Park
Big Data in Biochem and Molecular Biology Education
Justin Siegel, University of California Davis
CRISPR as a CURE in an Undergraduate Course
Heather Evans Anderson, Stetson University
Victoria Moore, Elon University and Martina Rosenberg, University of Connecticut, Session Organizers and Co-chairs
 
 

Monday, Apr. 8

 
 
ASBMB Alice and CC Wang Award in Molecular Parasitology Lecture and Symposium    
“Prison Break” Toxoplasma egress from infected cells is a tightly programmed event
Dominique Soldati-Favre, University of Geneva
Molecular Genetics for Cryptosporidium
Boris Striepen, University of Pennsylvania School of Veterinary Medicine
Environmental signals control transmission stage formation in Plasmodium falciparum
Nicolas Brancucci, Swiss Tropical and Public Health Institute
Metabolic interplay and flexibility in the intracellular Trypanosoma cruzi-host cell interaction
Barbara Burleigh, Harvard University T.H. Chan School of Public Health
 
Glycobiology    
Lectins from Bacteria and Fungi: Therapeutical Targets and Research Tools
Anne Imberty, French National Center for Scientific Research, Session Organizer and Chair
A New Model for the Biochemistry of Pectin Synthesis: GUATs Synthesize Diverse HG Glycans in Structurally and Functionally Distinct Plant Cell Wall Polymers
Debra Mohnen, Complex Carbohydrate Research Center, University of Georgia
Roles of Galectins in Innate Immunity: First Barrier or Trojan Horse?
Gerardo R. Vasta, Institute of Marine and Environmental Technology, UMB
Glycobiology of Host-microbe Interactions in the Gut
Nathalie Juge, Quadram Institute Bioscience
 
 
Inequities in Precision Medicine, organized by the ASBMB Minority Affairs Committee  
Populations from under-represented backgrounds are not adequately represented in clinical databases
Kathleen Barnes, University of Colorado School of Medicine, Session Co-organizer
Pharmacogenomics in Indigenous Populations
Katrina G. Claw, University of Washington

Leveraging Diversity for Population Genomic Health
Eimear Kenny, Icahn School of Medicine at Mount Sinai
Admixture and Asthma Pharmacogenetics
Victor Ortega, Wake Forest School of Medicine
Sonia Flores, University of Colorado School of Medicine, Session Co-organizer and Chair
 
 
Inflammation and Disease    
To Code Or Not To Code: What Is The Linc?
Richard Flavell, Yale University
Regulators of Inflammatory Responses
Thirumala- Devi Kanneganti, St. Jude Children's Research Hospital
Role of Inflammation in Control of Hepatic Lipid Metabolism-New Insights to the Pathogenesis of NASH
Michael Karin, University of California San Diego
Stopping the Leak: The Search for Gasdermin Inhibitors
Judy Lieberman, Session Organizer and Chair
Harvard Medical School/ Boston Children's Hospital
 
 
Journal of Lipid Research, an ASBMB Journal Symposium    
George Carman, Editor, JLR, Rutgers University, Session Organizer and Chair 
Complex genetic determinants of plasma lipoproteins
Jacqueline S. Dron, Robarts Research Institute
The structure of apoA-II on HDL reveals novel insights into its regulation of lipoprotein composition and function
John Melchior, University of Cincinnati
Small HDL, diabetes, and proinflammatory effects in macrophages
Vishal Kothari, University of Washington
Retinol Binding Protein 4 (RBP4) in Adipocytes and Obesity
Igor Shmarakov, Columbia University
Chlorolipids: Mediators and Outcome Predictors of Sepsis
Daniel Pike, Saint Louis University Health Science Center
 
 
Mitochondrial Biology    
The Interplay among Energetic Driving Forces 
Deborah Muoio, Duke Molecular Physiology Institute, Duke University
Altering Mitochondrial Bioenergetic Efficiency
Darrell Neufer, Session Organizer and Chair
East Carolina Diabetes &Obesity Institute, East Carolina University
Phosphatase Regulation of Mitochondrial Metabolism
David Pagliarini, Morgridge Institute for Research at UW-Madison
Metabolic Coordination of Tumor Suppression
Lydia Finley, Memorial Sloan Kettering Cancer Center
 
 
Molecular and Cellular Proteomics, an ASBMB Journal Symposium    
 Al Burlingame, Editor, MCP, UCSF, Session Organizer and Chair
The Role of Mass Spectrometry in the Advancement of HLA Epitope Prediction
Jennifer Abelin, Neon Therapeutics
Developing structural interactomics and its application in cell biology
Fan Liu, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
Proteomic Approaches to Better Understand Transcriptional Regulation
Sam Myers, Broad Institute
Proteoform dynamics in steady-state
Jana Zecha, Technical University of Munich

 
 
Molecular Medicineorganized by SEBM    
David Boothman and Warren Zimmer, Session Organizers and Co-chairs 
Session detail tba 
 
 
RNA Structural Dynamics    
Using Conformational Penalties to Assess the Structure Dependence of RNA Cellular Function
Hashim Al-Hashimi, Session Organizer and Chair
Duke University School of Medicine
Modification of mRNA by 2'-O-methylation
Christopher Lee Holley, Duke University School of Medicine
Quality Control in 40S Ribosome Assembly
Katrin Karbstein, The Scripps Research Institute
Regulation of Key Stages in the mRNA Lifecycle
Susan Wente, Vanderbilt University

 

 
 
Single Molecule Single Cell    
Fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase: single-molecule picometer-resolution nanopore tweezers (SPRNT)
Richard H. Ebright, Waksman Institute of Microbiology, Rutgers University
Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH
Long Cai, California Institute of Technology
Three-dimensional in situ sequencing of single cells in intact tissue
Xiao Wang, Stanford University
Single Cell Genomics: When Stochasticity Meets Precision
Sunney Xie, Peking University, Session Organizer and Chair
 
 
Structural Biology, organized by SEBM    
Tom Thompson, Session Organizer and Chair
Memorial Sloan Kettering Cancer Center
Session detail tba
 
 
Stem Cells and Therapy, organized by SEBM    
James King and Peter Stambrook, Session Organizers and Co-chairs
Session detail tba
 
 
Transitions at the Mid-Career Point, organized by the ASBMB Education and Professional Development Committee    
Using Scientific Teaching to Grow Your Academic Profile as an Educator and Scientist 
Richard A. Cardullo, UC, Riverside
Transitioning from Academia to Industry and Back Again 
Ivor T. Knight, Penn State, Behrend
The Post-tenure Sabbatical  
Victoria Moore, Elon University, Session Organizer and Co-chair
From Research to Faculty Developer
Martina Rosenberg, University of Connecticut, Session Organizer and Co-chair
Transitioning to Leadership in Higher Education 
Reema Zeineldin, Mercy College
 
 

Tuesday, Apr. 9

 
   
Aging and Longevity    
Mitochondria, Metabolism and Aging
Toren Finkel, University of Pittsburgh, Aging Institute
Oxidative Stress and Immune Cells as Drivers of Aging
Laura Niedernhofer, University of Minnesota, Session Organizer and Chair
The Role of Mitochondrial Peroxide Release in the Mechanisms Underlying Age-Related Sarcopenia
Holly Van Remmen, Oklahoma Medical Research Foundation
Lysosomal Metabolic Cues in Orchestrating Cellular and Organism Homeostasis
Meng Wang, Baylor College of Medicine
 
 
Biotherapies & Immunotherapies, organized by SEBM    
Faezin Farseneh, Session Organizer and Chair
Session detail tba
 
 
Breakthroughs In Plant Biochemistry    

The 4th Dimension of Transcriptional Networks: TIME
Gloria M. Coruzzi, Center for Genomics and Systems Biology, NYU
 

The Plant Social Network: Volatiles and Their Release
Natalia Dudareva, Purdue University, Session Organizer and Chair
 

Evolution and the Single Cell: Metabolic Diversity in Tomato
Robert Last, Michigan State University
 

Synthetic Evolution of C4 Photosynthesis
Andreas Weber, Heinrich Heine University
 

 
 
Circadian Rhythm    
Advantages and Disadvantages of Circadian Rhythms: A Tale of Two Microbes 
Michael Rust, University of Chicago, Institute for Genomics and Systems Biology
Circadian Control of Animal Physiology
Amita Sehgal, 
Session Organizer and Chair
University of Pennsylvania
Circadian Biology in Translation 
John Hogenesch, Cincinnati Children's Hospital Medical Center
Molecular Genetics of Human Sleep Behaviors 
Ying-Hui Fu, University of California San Francisco
 
 
DNA Repair, Recombination and Replication    
Responses to Replication Stress in Human Cells
Anja-Katrin Bielinsky, Session Organizer and Chair
University of Minnesota
Genomic and Proteomic Signatures of Replication Fork Collapse
Eric Brown, Abramson Family Cancer Research Institute
Replication origin licensing deficiency and genome instability during cell cycle re-entry from quiescence
Jean Cook, University of North Carolina , Chapel Hill
How Replication Stress Drives Genome Instability
Susan Forsburg, University of Southern California
 
 
Herbert Tabor Young Investigator Award Symposium    
George DeMartino, Associate Editor, Journal of Biological Chemistry, University of Texas Southwestern Medical Center, Session Organizer and Chair
Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
Evgeny Serebryany, Harvard Universtiy
Antibody Recognition of a Polysaccharide Common To Many Microbes and Biofilms
Caroline Soliman, RMIT University
Metabolic Origin of the Fused Aminoacyl tRNA Synthetase, Glutamyl-prolyl tRNA Synthetase
Sandeep M. Eswrappa, Indian Institute of Science
Mallostery: Ligand-dependent Misfolding as a Strategy for Protein Regulation
Margaret Wangeline, University of California, San Diego
The labile iron pool attenuates peroxynitrite-dependent damage and can no longer be considered solely a pro-oxidative cellular iron source
Fernando Cruvinel Damasceno, FFCLRP - Universidade de Sao Paulo
 
 
Lipid Metabolism    
Glycerolipid Intermediates as Signaling Mediators in Physiology and Disease
Brian Finck, Session Organizer and Chair
Washington University School of Medicine in St. Louis
The Regulation and Consequences of Lipid Droplet Catabolism
Doug Mashek, University of Minnesota
Regulation of Adipose Lipid Metabolism
Hei Sook Sul, Berkeley University of California
 Acetyl-CoA metabolism and the response to dietary sugar
Kathryn Wellen, Abramson Family Cancer Research Institute
 
 
Sirtuins in Cancer Biologyorganized by SEBM    
David Gius, Session Organizer and Chair
Session detail tba