Sessions

The latest research from across the interdisciplinary world of Biochemistry and Molecular Biology is in one place for you to explore. Daily, morning sessions feature invited presentations that will inform and inspire! Click the dates below for speaker details.

*denotes Symposia chair

Sunday, April 22

Biochemical Communication Between the Microbiome and the Host  

  • Andres Gomez, J. Craig Venter Inst. 
    Host microbe interactions in the primate gut: Implications for human origins
  • Lora Hooper*, UT Southwestern Med. Ctr.
    Metabolism, the microbiome, and the circadian clock
  • Eric Martens, Univ. of Michigan Med. Sch. 
    Bacterial metabolism in the colonic mucus layer: An axis between health and disease
  • Sarkis K. Mazmanian, Caltech 
    The gut microbiome connection to neurological disorders

Can We Target Aging? presented by the Society for Experimental Biology and Medicine  

  • Nir Barzilai*, Albert Einstein Coll. of Med.  
  • Judith Campisi, Lawrence Berkeley Nat'l Lib.  
  • Ana Maria Cuervo, Albert Einstein Coll. of Med.  
  • Thomas Rando, Stanford Univ.  

Intrinsically Disordered Proteins and their Regulation and Functions   

  • M. Madan Babu, Univ. of Cambridge 
    The role of disordered regions in GPCR-G protein signalling 
  • H. Jane Dyson*, Scripps Res. Inst. 
    How do intrinsically disordered viral proteins hijack the cell?
  • Rohit Pappu, Washington Univ. in St. Louis
    Disordered regions as modulators of function and phase behavior of multivalent proteins
  • Elizabeth Rhoades, Univ. of Pennsylvania 
    Investigating functions of dysfunctional proteins

Lipid Signaling and Metabolism  

  • Vytas Bankaitis, Texas A&M Health Science Ctr. 
    A Golgi lipid signaling pathway that controls neural stem cell polarity in the developing neocortex 
  • Rosalind Coleman, Univ. of North Carolina 
    Fatty acid compartmentalization
  • Jean Gruenberg, Univ. of Geneva 
    Endosomal lipids in trafficking and signaling
  • Michael Wakelam*, Babraham Inst.  
    Using lipidomics pathway analysis to identify potential therapeutic targets

Novel Enzymology  

  • Ron Raines*, Univ. of Wisconsin-Madison 
    Ribonuclease: From kcat/KM to the Clinic
  • Dan Tawfik, Weizmann Inst.  
    How do enzymes evolve?
  • Paul Thompson, Univ. of Mass. Med. Sch.  
    Picking the PADlock:  Chemical strategies to interrogate the Protein Arginine Deiminases
  • Suzanne Walker, Harvard Med. Sch. 
    O-GlcNAC transferase: Diverse outcomes from the same active site

RNA Form and Function  

  • Juan Alfonzo, Ohio State Univ. 
  • Lydia Contreras, UT, Austin 
  • Andrew Ellington, Case Western Univ.  
  • Ya-Ming Hou, Thomas Jefferson Univ.   
    NA methylation: A mechanism to regulate gene expression

Strategically Building Your CV at Every Career Stage  

  • Nicquet Blake, UT Health San Antonio  
  • Mary CanadyComprendia, LLC and San Diego Biotechnology Network  
  • Robert To, Bayer HealthCare  

Discussion Panel: Strategically Building Your CV at Every Career Stage  

  • Nicquet Blake*UT Health San Antonio  
  • Rachell Booth, Univ. of the Incarnate Word  
  • Mary Canady, Comprendia, LLC and San Diego Biotechnology Network  
  • Marvin PayneLa Sierra Univ., (Moderator)  
  • Robert To, Bayer HealthCare  

Synthetic Biology presented by the Society for Experimental Biology and Medicine  

  • Julius Lukus, Northwestern Univ.
    Teaching ancient molecules new tricks: Unlocking the potential of RNA synthetic biology
  • Lulu Qian, Cal Tech
    A cargo-sorting DNA robot
  • Peter G. Schultz, Scripps Research Inst.
    Playing with the molecules of life
  • Peter Stambrook*, Univ. of Cincinatti    
  • Yuval Elani, Imperial Col., London
    Engineering membrane-bound microsystems as artificial cells
 

Workshop: Strategically Building Your CV at Every Career Stage  

  • Nicquet Blake, UT Health San Antonio  
  • Rachell Booth, Univ. of the Incarnate Word  
  • Mary Canady, Comprendia, LLC and San Diego Biotechnology Network  
  • Marvin Payne, La Sierra Univ., (Moderator)    
  • Robert Toi, Bayer HealthCare  
 

Monday, April 23

Adapting Proteostasis to Ameliorate Neurodegenerative Diseases  

  • Jason Gestwicki, Univ. of California, San Francisco 
    Targeting protein-protein interactions in chaperone complexes to normalize proteostasis
  • Jeffrey Kelly*, Scripps Inst.  
    Adapting proteostasis to ameliorate neurodegenerative diseases
  • Richard Morimoto, Northwestern Univ.  
    The biology of proteostasis in aging and disease
  • Marina Ramirez-Alvarado, Mayo Clinic 
    Systemic misfolding of immunoglobulins in the test tube and in the cell

Communicating Scientific Ideas to Novice Audiences  

  • Paul Craig, Rochester Inst. of Tech.  
  • Nana Lee, Univ. of Toronto  
  • Arthur Lupia, Univ. of Michigan  

Discussion Panel: Communicating Scientific Ideas to Novice Audiences  

  • Rachell Booth, Univ. of the Incarnate Word (Moderator)  
  • Paul Craig, Rochester Inst. of Tech.  
  • Nana Lee, Univ. of Toronto  
  • Arthur Lupia, Univ. of Michigan  
  • Marvin Payne, La Sierra Univ.       

Environmental Health, Biomarkers and Precision Medicine presented by the Society for Experimental Biology and Medicine   

  • Russ Altman
    Impact of biomarkers on precision medicine
  • Rob CaliffBirmingham Univ. UK
    Minimally-invasive biomarkers of neurotoxicity: Application to drug development
  • Stephania Cormier*Univ. of Tennessee Health Sci. Ctr.  
  • Ken RamosUniv. of Ariz.  
  • Dan Shaughnessy, Food and Drug Administration
    Precision prevention
  • Bill Slikker*Food and Drug Administration  

Glycobiology and Functional Glycomics   

  • Markus Aebi, ETH Zürich 
    Precisely heterogeneous - the making of N-glycoproteins 
  • Linda C. Hsieh-Wilson*, Caltech 
    The sweeter side of cell signaling
  • Lara K. Mahal, New York Univ. 
    Decoding glycans: The signal within the noise
  • Natasha Zachara, Johns Hopkins Univ. Sch. of Med. 
    Mapping the O-GlcNAc-Cytoprotective network

New Insights into the Links Between Metabolism and Disease  

  • Lewis C. Cantley*, Weill Cornell Medicine 
    Obesity, insulin resistance and cancer: The PI3K connection
  • Ralph J. DeBerardinis, UT Southwestern Med. Ctr.
    Metabolic reprogramming and its role in causing human diseases
  • Ronald Evans, Salk Inst. HHMI 
    Targeting the pancreatic cancer ecosystem
  • M. Celeste Simon, Univ. of Pennsylvania, Perelman Sch. Of Med. 
    Metabolism, inflammation, and tumor progression

Regenerative Medicine presented by the Society for Experimental Biology and Medicine   

  • James Kang*Inst. for Regenerative Med., Sichuan Univ. Med. Sch.  

RNA in Human Disease  

  • Omar I. Abdel-Wahab, Memorial Sloan Kettering Cancer Ctr.  
    Understanding and targeting spliceosomal gene mutations in cancer
  • Montserrat C. Anguera, Univ. of Pennsylvania, Sch. of Vet. Med.  
  • Blanton S. Tolbert, Case Western Res. Univ. 
  • Gene Yeo, UCSD   
    Comprehensive studies of protein-RNA complexes yields insights into neurodegeneration 

Systems Biology and Proteomics  

  • Steven A. Carr, Broad Inst.  
    New approaches for localization of proteins and interaction partners in cells with high spatial resolution
  • Ileana M, Cristea*, Princeton Univ.  
    Hybrid experimental-mathematical methods for understanding dynamic proteome organization during viral infections
  • Kevin White, Univ of Chicago 
    TBD  
  • Heng Zhu, Johns Hopkins Univ. Sch. of Med.   
    DNA methylation presents distinct binding sites for human transcription factors  
 

Workshop: Molecular Visualization 

  • Jeffrey L. Mills, Rochester Inst. of Tech.
  • Rachel Booth, Univ. of the Incarnate Word 
  • Marvin Payne, La Sierra Univ. 
 

Tuesday, April 24

Advances in Single Cell Omics  

  • Ibrahim I. Cissé,  MIT 
    Super-resolution imaging of transcription in live mammalian cells
  • James H. Eberwine*, Univ, of Pennsylvania, Perelman Sch. of Med. 
    Multimodal single mouse and human cell 'Omics: Is variability distinct across cellular modalities?
  • Amy E. Herr, Univ. of California, Berkeley  
    Electrophoretic cytometry: High-selectivity measurement of isoforms using microfluidics
  • Barbara J. Wold,, Caltech 
    The developing limb: One cell at a time

Biochemistry of Autophagy and Organelle Trafficking  

  • Kun-Liang Guan*, Univ. of California, San Diego 
    Nutritional regulation of the Hippo pathway
  • James H. Hurley, Univ. of California, Berkeley 
    Initiation, targeting and sculpting of the phagophore
  • Reuben J. Shaw, Salk Inst.  
    AMPK: Mechanisms of cellular energy sensing and restoration of metabolic balance
  • Li Yu, Tsinghua Univ. 
    Migrosome and migrocytosis

Novel Antibiotics and Alternatives presented by the Society for Experimental Biology and Medicine   

  • Dan Hassett*, Univ. of Cincinnati  

Plants Do it All     

  • Sean Cutler*, Univ. of California, Riverside 
    Engineering plant signal transduction for water smart crops
  • Beronda L. Montgomery, Michigan State Univ.  
    Spatiotemporal phytochrome-dependent regulation of photosynthesis and growth
  • Elizabeth Sattely, Stanford Univ.  
    Discovery and engineering of plant chemistry for plant and human health
  • Daniel Voytas, Univ. of Minnesota 
    Opportunities afforded by editing the plant genome

Signal Transduction, Pathogenesis and Disease  

  • K. Heran Darwin, New York Univ. Sch. of Med. 
    Proteasomal regulation of hormone signaling in Mycobacterium tuberculosis
  • Tracy Handel, UCSD 
  • Andrew Kruse, Harvard Med. Sch.  
    New technologies to interrogate G protein-coupled receptor signaling
  • Zhao-Qing Luo, Purdue Univ.  
    Single protein-catalyzed ubiquitination: Chemistry and implications in cell signaling
  • Kim Orth*, UT Southwestern Med.Ctr., HHMI (ASBMB-Merck Award Lecturer)

RNA-mediated Epigenetics   

  • Vahe Bandarian, Univ. of Utah
  • Peter Dedon, MIT 
    SMRT-Cappable-seq reveals complex operon variants in bacteria
  • Laurence Ettwiller, New England Biolabs 
  • Samie Jaffrey, Weill Cornell Med. Col. of Cornell Univ.  
    The dynamic epitranscriptome: Control of mRNA fate and function by nucleotide modifications

Structural Biology presented by the Society for Experimental Biology and Medicine   

  • Tom Thompson*, Univ. of Cincinatti  

Advances in Single Cell Omics  

  • Ibrahim I. Cissé, MIT
    Super-resolution imaging of transcription in live mammalian cells
  • James H. Eberwine*, Univ, of Pennsylvania, Perelman Sch. of Med. 
    Multimodal single mouse and human cell ‘Omics: Is variability distinct across cellular modalities?
  • Amy E. Herr, Univ. of California, Berkeley 
    Electrophoretic cytometry: High-selectivity measurement of isoforms using microfluidics
  • Barbara J. Wold, Caltech    
    The developing limb: One cell at a time  
 

Wednesday, April 25

Biochemical Basis for Epigenetics and Chromatin Remodeling   

  • Benjamin A. Garcia*, Univ. of Pennsylvania Sch. of Med. 
    Quantitative proteomics for understanding the histone code
  • Tatiana Kutateladze, Univ. of Colorado, Denver 
    Reading epigenetic marks
  • Peter Lewis, Univ. of Wisconsin 
    Nucleosome-independent functions for histone H3.3
  • Tom W. Muir, Princeton Univ. 

Enzyme Dynamics in Catalysis, Spectroscopy and Theory  

  • Michael D. Fayer, Stanford Univ. 
    Fast dynamics of proteins observed with two dimensional vibrational echo spectroscopy
  • Sharon Hammes-Schiffer*, Univ. of Illinois at Urbana-Champaign 
    Proton-coupled electron transfer in soybean lipoxygenase: Hydrogen tunneling and conformational motions
  • Lewis E. Kay, Univ. of Toronto 
    Seeing the invisible by NMR spectroscopy

Metabolomics and Lipidomics   

  • Christian Metallo, Univ. of California, San Diego 
    Exploring links between amino acid and lipid metabolism
  • Daniel Nomura*, Univ. of California, Berkeley 
    Chemoproteomic approaches to map drivers of disease
  • Gary Patti, Washington Univ. at St. Louis 
    Shrinking the metabolome for systems biology
  • Eranthie Weerapana, Boston Coll. 
    Chemical-proteomic strategies to investigate reactive cysteines

Metals in Biology   

  • Michael A. Marletta, Univ. of California, Berkeley 
    Sensing nitric oxide
  • Caryn E. Outten, Univ. of South Carolina 
    Glutaredoxins, glutathione, and iron regulation
  • Amy Palmer*, Univ. of Colrado, Boulder 
    Discovery of new roles for zinc in biology from quantitative mapping of zinc in mammalian cells
  • Eric Skaar, Vanderbilt Univ. Sch. of Med.  
    The struggle for metal at the host-pathogen interface