May 4, 2012 — In this podcast, we hear an interview with Myron Goodman from the University of Southern California and David Rueda from Wayne State University, who talk about the collaboration which led to their JBC Paper of the Week, Singled-stranded DNA Scanning and Deamination by APOBEC3G at Single Molecular Resolution. The interview and paper focus on the immunogenic effects of single-stranded DNA scanning enzymes; in particular, with relation to HIV infectivity.