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July 23, 2015 — The National Science Foundation has awarded the ASBMB a grant of half a million dollars to support a comprehensive mentoring program for postdoctoral fellows and early-career faculty. The program focuses on grantsmanship skills and career-development strategies. It also promotes diversity in the scientific workforce by supporting underrepresented minority postdoctoral scientists and new assistant professors in their efforts to secure research funding. More...
On our cover, we feature a story about a rare brain tumor that always has seemed unstoppable.
BONUS: RSVP for a compelling ASBMB Live Google+ Hangout about DIPG and the discovery that has given researchers hope that someday this rare pediatric brain cancer can be tamed.
July 14, 2015 — Four Minireviews deal with aspects of the α-ketoglutarate/iron dependent dioxygenases in this eighth Thematic Series on Metals in Biology. The Minireviews cover a general introduction and synopsis of the current understanding of mechanisms of catalysis, the roles of these dioxygenases in post-translational protein modification and de-modification, the roles of the ten-eleven translocation (Tet) dioxygenases in the modification of methylated bases (5mC, T) in DNA relevant to epigenetic mechanisms, and the roles of the AlkB-related dioxygenases in the repair of damaged DNA and RNA.
Read all of the articles in this series here
July 14, 2015 — Over the past half century, The Journal of Biological Chemistry has been the venue for many landmark publications on the topic of G protein coupled receptors (GPCRs, also known as 7 transmembrane receptors). The GPCR superfamily in humans is comprised of about 800 members, and is the target of about one third of all pharmaceuticals. Most of these drugs target a very small subset of GPCRs, and do so by mimicking or competing with endogenous hormones and neurotransmitters. This thematic mini-review series examines some emerging trends in GPCR drug discovery.
The Howard Hughes Medical Institute (HHMI) announced 15 scientist-educators who have been named HHMI professors. Each will receive $1 million over five years "to create activities that integrate their research with student learning in ways that enhance students' understanding of science." Forty scientists have been named HHMI professors since the program began in 2002.
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