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Single-stranded DNA scanning enzymes
May 4, 2012 — In this podcast, we hear an interview with Myron Goodman from the University of Southern California and David Rueda from Wayne State University, who talk about the collaboration which led to their JBC Paper of the Week, Singled-stranded DNA Scanning and Deamination by APOBEC3G at Single Molecular Resolution. The interview and paper focus on the immunogenic effects of single-stranded DNA scanning enzymes; in particular, with relation to HIV infectivity.

JBC Podcast: Editor-in-Chief Martha Fedor on the JBC Best of 2011April 5, 2012 — In this podcast, we hear an interview with JBC Editor-in-Chief Martha Fedor, who talks about the journal’s new honor, the Best of 2011. Of the more than 4,000 articles published last year in The Journal of Biological Chemistry, 20 were selected, each representing a different affinity group.

Discovering the role of TDP-1 in regulating protein homeostasis and agingMarch 9, 2012 — In this JBC podcast, we hear an interview with Jiou Wang from The Johns Hopkins University, who talks about his group’s Paper of the Week: “Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Lifespan.“ The paper and interview focus on the connection between neurodegeneration and aging.

Structure of Key Player in Malaria DeterminedJanuary 3, 2012 - In this JBC podcast, we hear an interview with Joseph Jez from Washington University in Saint Louis, who talks about his group's Paper of the Week, "Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an anti-parasitic drug target." The paper and interview discuss the role of lipid biosynthesis in malaria.

Teasing out ATP's role in immune responsesNov. 22, 2011 -- In this podcast we hear an interview with Peter Hanley from the Institute for Molecular Cell Biology in Münster, Germany, who talks about his group's Paper of the Week: "Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to C5a is PI-3K and p38 MAPK-independent." The paper and interview investigate the role of ATP in inducing the chemotactic response of macrophages during inflammation.

JBC News: Mass spec means more than mass dataAug. 16, 2011 -- In this podcast, we hear from JBC Associate Editor Peter Guengerich about a recent thematic minireview series on the biological applications of mass spectrometry. The discussion covers highlights from the minireviews in the series and the history of mass spec and the JBC.

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