Revisiting metals in the fifth edition of the thematic minireview series
The Journal of Biological Chemistry’s thematic minireview series “Metals in Biology” is back for a fifth edition. This series features metals in biochemistry and human health and is coordinated by F. Peter Guengerich of Vanderbilt University, a JBC associate editor. The first two editions of “Metals in Biology” discussed iron, copper, selenium, zinc, nickel, vanadium and arsenic, the third focused on iron homeostasis and eukaryotic cells, and the fourth concentrated on metal transport and homeostasis. The latest collection of minireviews covers the molybdenum prosthetic group, or pterin Moco; the biosynthesis of M-cluster molybdenum prosthetic group of nitrogenase; the biosynthesis of the nickel-based metallocenter of the enzyme urease; several of the processing, transport and medical aspects of cobalamins; and the growing roles of heme sensor proteins.