July 2012
 

TGF-β regulated brown adipocyte induction in white adipose tissue


Recent identification of active brown fat in adult humans has stimulated research into the role of brown adipocytes in energy homeostasis.

 

Thematic minireview series highlights metals in biology


Read about the Journal of Biological Chemistry's fourth thematic minireview series about the role of metals in biochemistry and human health. The series was coordinated by JBC Associate Editor F. Peter Guengerich.

 

Crystal structure of bacterial enzyme reveals a potential target for new antibiotics


The rise of antibiotic resistance has researchers searching for new targets in pathogenic bacteria. One promising target, detailed in a recent JBC Paper of the Week, is a key enzyme that is essential for isoprenoid synthesis in most bacteria.

 

Despite millions of years of evolution, the function of lipid droplets remarkably has stayed the same


A review published in the July issue of the Journal of Lipid Research explores how proteomic studies on lipid droplets in a wide range of organisms provide evidence that the function of some of the compounds contained in these droplets has been conserved, despite millions of years of evolution. The review is part of an ongoing thematic series on lipid droplet storage and metabolism.

 

Testing drug toxicity earlier in the process


A recent article in the journal Molecular & Cellular Proteomics describes a sensitive approach at the molecular level to tell if a potential drug will be toxic early in the development process.

 

What’s up with accreditation: a progress report


Peter Kennelly, head of the biochemistry department at Virginia Tech and chairman of the ASBMB Education and Professional Development Committee, updates us on the status of the society's future accreditation program.

 

Remembering Tuskegee


Squire Booker traces the historical steps that led to the tragic, 40-year-long, government-sponsored Tuskegee syphilis study as well as the changes in public health and medical research policy that have come about as a result.

 

Spearheading science-outreach efforts


Columnist and Public Outreach Coordinator Geoff Hunt tells how all ASBMB members can help spread the word and increase science literacy across the country.

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