August 2010
 

[JBC] Better Bispecific Antibodies


Biobits---JBC1---thumbDevelopment of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling

Janet Jackman, et al.

J. Biol. Chem. (2010) 285, 20850 – 20859
 

[JBC] PKA Localization Is Pivotal in the Heart


Biobits---JBC2---thumbDisruption of Protein Kinase A Localization Using a Trans-activator of Transcription (TAT)-conjugated A-kinase-anchoring Peptide Reduces Cardiac Function

Hemal H. Patel, et al.

J. Biol. Chem, published online June 26, 2010
 

[JLR] A Disruption Is Statin’


Biobits---JLR---thumbHigh Dose Atorvastatin Causes a Rapid, Sustained Increase in Human Serum PCSK9 and Disrupts Its Correlation with LDL Cholesterol

Greg Welder, et al.

J. Lipid Res., published online June 5, 2010
 

[MCP] Penicillin: Gone Industrial


Biobits---MCP---thumbProteome Analysis of the Penicillin Producer Penicillium chrysogenum: Characterization of Protein Changes during the Industrial Strain Improvement

Mohammad-Saeid Jami, et al.

Mol. Cell. Prot. (2010) 9, 1182 – 1198
 

How to Prepare for a Job in Industry


Career-Insights-iconBY TERTIUS DE KLUYVER 

Industry insiders give tips on how to apply for a job in industry, what to expect during the interview and how to maximize your chances of landing a position.

 

Meeting Theme: Lipid and Membrane Metabolism


Meetings-iconBY VYTAS A. BANKAITIS AND TERESA M. DUNN 

At the ASBMB 2011 annual meeting, the "Lipid and Membrane Metabolism" theme will cover phosphoinositides, sphingolipids, phospholipases D and neutral lipids.

 

Meeting Theme: Metabolism and Disease


Meetings-iconBY BARBARA E. CORKEY AND MARC PRENTKI 

The "Metabolism and Disease" meeting theme will cover mitochondrial dysfunction, information transmission, signal transduction and cancer. There also will be a special workshop, titled “New Tools to Study Mitochondrial Function.”

 

Meeting Theme: Signal Transduction from the Plasma Membrane to the Nucleus


Meetings-iconBY CHARLES E. SAMUEL AND KAREN L. O’MALLEY 

Sessions in the ASBMB annual meeting theme "Signal Transduction from the Plasma Membrane to the Nucleus" will look at janus kinase STAT transcription factors, intracellular signaling, innate immunity and circadian rhythms.

 

Outsourcing to Emerging Global Markets


world-science-iconBY NICK ZAGORSKI 

Outsourcing to emerging global markets like China, India and Brazil is rapidly becoming popular in the biotechnology and pharmaceutical industry. Here, Richard Soll talks about the past, present and future of research and development outsourcing. 

 

Overcoming Isolation in Science


minority-affairs-iconBY SQUIRE J. BOOKER

Minorities in science often have a hard time finding other minorities to connect with. The ASBMB Minority Affairs Committee has launched several initiatives in an effort to eliminate some of this isolation.  

 

Professional Master’s Education


Education-iconBY SHEILA TOBIAS 

Increasing numbers of students are getting professional master's degrees in the biosciences, preparing them for jobs in the nation's tech based workforce.  

 

Skeletal Muscle Lipid Metabolism


lipid-iconBY DEBORAH M. MUOIO 

Deborah M. Muoio explains how her laboratory has employed a targeted metabolomics approach to survey several two state models of insulin sensitivity.

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