July 2010
 

[ASBMB] Did You Know?


Biobits---President---thumbSince its founding in 1906, the American Society for Biochemistry and Molecular Biology has had 82 presidents.

For more information about ASBMB presidents, go to the ASBMB history site.

 

[JBC] Nab-bing onto Gfd1


Biobits---JBC---thumbStructural Basis for the Function of the Sacchromyces cerevisiae Gfd1 Protein in mRNA Nuclear Export

Chao Zheng, Milo B. Fasken, Neil J. Marshall, Christoph Brockmann, Max E. Rubinson, Susan R. Wente, Anita H. Corbett and Murray Stewart

J. Biol. Chem. published online May 12, 2010
 

[JLR] Good Cholesterol, Good Lungs


Biobits---JLR---thumbGenetic Deletion of Apolipoprotein A-I Increases Airway Hyperresponsiveness, Inflammation and Collagen Deposition in the Lung

Weiling Wang, Hao Xu, Yang Shi, Sandhya Nandedkar, Hao Zhang, Haiqing Gao, Thom Feroah, Dorothee Weihrauch, Marie L. Schulte, Deron W. Jones, Jason Jarzembowski, Mary Sorci-Thomas and Kirkwood A. Pritchard, Jr.

J. Lipid Res. published online May 24, 2010
 

[MCP] Biomarker Pipeline for Ovarian Cancer


Biobits---MCP---thumbUse of a Single Chain Antibody Library for Ovarian Cancer Biomarker Discovery

Arturo B. Ramirez, Christian M. Loch, Yuzheng Zhang, Yan Liu, Xiaohong Wang, Elizabeth A. Wayner, Jonathon E. Sargent, Sahar Sibani, Eugenie Hainsworth, Eliseo A Mendoza, Ralph Eugene, Joshua LaBaer, Nicole D. Urban, Martin W. McIntosh and Paul D. Lampe

Mol. Cell. Proteomics, published online May 13, 2010
 

A Career in Research Administration


Career-Insights-iconBY DAVID TAYLOR

David Taylor explains how he ended up in a career in research administration at The Children’s Hospital of Philadelphia Research Institute and why he finds his "strange new world" so appealing. 

 

A Look at the PSI Biology Initiative


Meetings-iconBY PETER C. PREUSCH 

A special session at the 2010 ASBMB meeting in Anaheim looked at the new biology phase of the Protein Structure Initiative a large scale effort to accelerate discovery in structural genomics. This article details some of the topics that were discussed at that meeting.

 

Controling Toxic Chemicals: The European Union's REACH Legislation


world-science-iconBY TERTIUS DE KLUYVER

A look at the European Union's REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) legislation, enacted to address public demand for the control of toxic chemicals used in manufacturing and agriculture. 

 

Funding Research and Education


Education-iconBY PETER J. KENNELLY

Although we are facing a funding crisis, divorcing undergraduate education from research will not insure continued innovation and success in the laboratory and the classroom, as some suggest.

 

Meeting Theme: DNA Replication, Recombination and Repair


Meetings-iconBY JOANN SWEASY AND MARLENE BELFORT  

The four sessions in the "DNA Replication, Recombination and Repair" 2011 annual meeting theme will focus on genomic instability, chromosome dynamics and gene therapy, processing of non-B form DNA by the cell and RNA as a mediator of genome plasticity. 

 

Meeting Theme: Protein Synthesis and Degradation


Meetings-iconBY IVAN DIKIC AND RAMANUJAN HEGDE

The sessions in the "Protein Synthesis and Degradation" theme will cover the ribosome and protein translation, membrane protein biosynthesis, protein folding and quality control and protein aggregation and autophagy. 

 

Meeting Theme: Structure, Mechanism and Regulation in Enzyme Catalysis


Meetings-iconBY SQUIRE J. BOOKER AND L. MARIO AMZEL

The 2011 annual meeting theme "Structure, Mechanism and Regulation in Enzyme Catalysis" will look at metals and redox chemistry, sulfur chemistry and biological redox, processive enzymes and kinases, phosphatases, and phosphorus in biological reactions.

 

Meeting Theme: Transcription and Chromatin


Meetings-iconBY KAROLIN LUGER AND QIANG ZHOU  

The "Transcription/Chromatin" theme will contain sessions titled: "Structural Transitions in Chromatin - An Exploration of Mechanisms," "Alternative Chromatin Structures," "RNA Polymerase Pausing and Elongation" and "Transcriptional Regulation in Growth, Differentiation and Diseases."

 

Roles of Phosphoinositides in Plants


BY WENDY F. BOSS

lipid-iconPhosphoinositides play important roles in both environmental response and metabolism in plants. This article looks at some of these molecules and the parts they play.

 

The Current Postdoctoral Experience


Education-iconBY ANTHONY J. BAUCUM II

An overview of current postdoctoral demographics and the challenges faced by many of today’s postdocs. 

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