December 2013

New biomarker for diagnosing patients with degenerative eye disease

In a study published in the December issue of the Journal of Lipid Research, Rong Wen, Byron L. Lam and Ziqiang Guan of the Bascom Palmer Eye Institute at the University of Miami report that patients with retinitis pigmentosa have increased levels of the compound dolichol-18, compared with healthy individuals.


Harry F. Noller’s ‘Reflections’

Harry F. Noller reflects in The Journal of Biological Chemistry on his lifelong pursuit of cracking the functionality of the ribosome, via its structure, culminating in the aha moment when a “chubby L-shaped density appeared in exactly the position that we had predicted for the A site.”


Long-distance relationships in gene regulation

In a recent minireview in The Journal of Biological Chemistry, Zong Wei and colleagues at the University of Southern California give an extensive account of the significance and biological implications of long-range chromosomal interactions.


Keeping up with kinases

In a paper in a recent issue of Molecular & Cellular Proteomics, a team led by W. Andy Tao at Purdue University described a proteomic approach to identify directly the substrates of tyrosine kinases.

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