June 2010

[MCP] Mass Spectrometry and the Evolution of Proteomics

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Biobits---MCPThe importance of mass spectrometry in the development of proteomics is well documented by the proliferation of publications, meetings, conferences and other forums devoted to it. The International Symposium on Mass Spectrometry in the Health and Life Sciences represents one outstanding example; started in 1984 at the University of California, San Francisco and held biennially since 2001, there now have been nine meetings in this series, most recently in August 2009. In recognition of the meeting, the May issue of Molecular and Cellular Proteomics contains 21 articles from the 9th symposium. These articles represent the broad scope of topics covered and demonstrate the central role that mass spectrometry plays in deciphering the molecular understanding of biology. The articles include descriptions of new mass spectrometry applications and software that give more extensive and sensitive analyses of complex protein mixtures; applications to difficult biological problems such as stem cell biology and protein/protein interactions; neurobiological studies in higher systems and translational applications like biomarkers and forensic science. Although it showcases only a handful of the fields of study to which proteomics has made and will continue to make significant contributions, this special issue reinforces mass spectrometry’s place as one of the premier tools in current biological and biomedical research.

Highlights from the 9th International Symposium on Mass Spectrometry

Mol. Cell. Proteomics, published May 2010

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