May 2011

Patient-oriented lipid research

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The Journal of Lipid Research has an important section that highlights clinical studies of lipids called “Patient-Oriented and Epidemiological Research.” The first two papers in this category were published in Sept. 2006 and included an investigation of apolipoprotein A-IV in patients with decreased kidney function and studies on a drug with hypoglycemic action in healthy, non-diabetic subjects. Since then, JLR’s section on patient-oriented and epidemiological research has seen articles on obesity, diabetes, atherosclerosis, coronary heart disease, liver disease and many other clinically important topics. We encourage researchers who study lipids in human subjects to submit their research to JLR for consideration.

This month’s issue of the journal features a variety of topics in clinical research. JLR is quickly becoming known for publishing high-quality papers in the area of lipidomics, and the May issue is no exception, with papers such as the one by Mario Ollero of INSERM, France, titled “Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.” Also in the May issue, Charles B. Stephensen of the University of California, Davis, has a paper focusing on nutritional studies titled “ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation,” and Ting-Ting Tang of Union Hospital in China presents clinical data on a statin’s effects on people with arthritis. Marjan Shafaati of the Karolinska Institutet in Sweden also shares results on the role of the neurotoxin oxysterol 27-hydroxycholesterol in neurodegeneration.

Mary L. Chang ( is the managing editor of the Journal of Lipid Research.

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