In 2000, Aebersold co-founded the Institute for Systems Biology in Seattle, which has been a leading proponent of the application of proteomic methods and techniques to understanding cell biology at an integrated level. In 2004, he returned to his native Switzerland as a professor at the Swiss Federal Institute of Technology Zurich and the University of Zurich to continue these efforts.
He was one of the earliest investigators to appreciate the importance and power of mass
spectrometry in analyzing peptide and protein samples and has been one of the pioneers in the use of this technology.
Aebersold also has received substantial recognition and numerous awards, including the ASBMB Herbert A. Sober Award in 2010, for his studies, responsibilities and associations. He serves on seven editorial boards and was one of the founding associate editors of MCP (and has published in the journal 50 of his more than 500 contributions). His lecture at the 10th HUPO Congress is titled “The Organization of the Proteome in Time and Space” and reflects his continued interest in expanding our appreciation of living systems by better understanding the dynamics of the proteome.
Both Mann and Aebersold are prominent members of a small cadre of innovators who have birthed the field of proteomics and are now driving its still largely undeveloped potential to ask (and answer) increasingly complex questions. They perfectly represent the power of mass spectrometry and related technologies to eventually make good on the early promises of proteomics (and the other omic sciences) to make significant inroads into the pressing problems associated with health, energy, food supply and the environment. As such, they are ideally suited to initiate the MCP lecture program. We look forward to this tradition continuing at other meetings and symposia.
- 1. Bradshaw, R. A. and Burlingame, A. L. (2010). Technological innovation revisited, Mol Cell Proteomics 9, 2335 – 2336
- 2. Special Library Association’s 2009 ranking of the top 100 journals in biology and Medicine: http://units.sla.org/division/dbio/publications/resources/dbio100.html
- 3. Ong, S. E.; Blagoev, B., Kratchmarova, I.; Kristensen, D. B.; Steen, H.; Pandey, A.; and Mann, M. (2002). Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 1, 376 – 386
Ralph A. Bradshaw (firstname.lastname@example.org) and Al L. Burlingame (email@example.com) are co-editors of Molecular & Cellular Proteomics.