In our cover story, we learn about Jennifer Doudna's groundbreaking work on CRISPR and Cas9 and about her close relationship with her lab manager, who she says has played a pivotal role in her group's success. Thinking about making the jump from a faculty position to a spot in your institution's administration? See our second article in a series about moving to "the dark side" by Benjamin D. Caldwell and Mary Huff. Meanwhile, contributor Andrew Hollenbach writes about overcoming a significant roadblock on his career path: panic attacks. And Milton J. Cormier and Richard O. McCann write about the role of the Cormier lab in the cloning and expression of the GFP gene. Last, but not least, don't miss the first "President's Message" by ASBMB President Steven McKnight, who, by the way, will participate in a live-streamed Q&A session Aug. 11. Get your questions ready!