News from the Hill


Twenty students joined members of the Public Affairs Advisory Committee for the ASBMB’s annual Hill Day, an opportunity to meet members of Congress and advocate for continued federal funding of biomedical research.

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Member update


Awards, promotions and more. Find out what's going on in the lives of ASBMB members. Send us your updates

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New ASBMB members


The American Society for Biochemistry and Molecular Biology welcomes new members.

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Retrospective


Sandra Weller and Lawrence Rothfield remember their friend and colleague — a prominent biomedical researcher, a trailblazer for women in science and a former president of the American Society for Biochemistry and Molecular Biology.

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In remembrance


The ASBMB learned this year about the deaths of these members.

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Lipid news


Hiromi Sesaki and colleagues at the Johns Hopkins School of Medicine write about their work in mitochondrial division and fusion, with a focus on the role of three GTPases; mutations in these enzymes lead to disorders that affect the nervous system.

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For May, it’s in your bones


May is arthritis awareness month, so Quira Zeidan focuses on the elements calcium and phosphorus, the two components of the mineral salt hydroxyapatite, which makes up about 65 percent of human adult bone mass.

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JBC: Bacterial drug synergies


While on the hunt for a molecule with therapeutic potential, Peter Mrak and his colleagues made a sweeping discovery: Every known isolate that produces the drug rapamycin can make a second compound that enhances rapamycin’s effect. They write about their work in the Journal of Biological Chemistry.

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JBC: The mystery of metformin


Sixty years after Jean Sterne discovered that metformin lowers blood glucose levels in people with Type 2 diabetes, researchers are still trying to figure out the drug’s molecular mechanism. Martin Spiering writes about two seminal studies in the Journal of Biological Chemistry that attempted to address that problem, now recognized as JBC Classics.

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MCP: How to catch ovarian cancer


In the journal Molecular & Cellular Proteomics, researchers in Israel report that by isolating microvesicles from uterine fluid and comparing thousands of proteins, they have developed a diagnostic tool for a cancer that’s often discovered too late for effective treatment.

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JLR celebrates diamond jubilee


The Journal of Lipid Research marks its 60th year of publication by inviting more than 50 researchers to share updates on their work. The first set of reviews looks at the role of lipids in pharmaceutical science, rare diseases, immune signaling and metabolism. 

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From the journals


Volatile organic compounds released by herbivore-infested plants. Protein phosphorylation in sperm development. Sphingosine in mitochondrial dysfunction after traumatic brain injury. Read about these and other topics in our round-up of papers published in the Journal of Biological Chemistry, the Journal of Lipid Research, and Molecular & Cellular Proteomics.

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Circulating oxysterol levels


Oxygenated metabolites of choles­terol play important roles in mediating cholesterol and lipid metabolism. By measuring the blood levels of these oxysterols in breast cancer pa­tients before and after tumor removal, F. Peter Guengerich and colleagues found that certain concentrations changed, some in surprising ways.

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