ASBMB to host symposium
on transcriptional regulation

Published February 01 2018

The RNA polymerase II enzyme transcribes all protein-coding genes and many noncoding RNAs in eukaryotic genomes. Regulation of RNA polymerase II activity requires a host of protein and nucleic acid factors, including genomic DNA itself, which is assembled into chromatin. Precise regulation of RNA polymerase II function, including processing of its RNA transcripts, is essential for cell differentiation and development, and defects in these regulatory mechanisms underlie many human diseases. Recent advances in biochemical, cellular and biophysical methods have allowed for unprecedented insights about RNA polymerase II transcription and its regulation by chromatin and other factors.

Given the importance of RNA polymerase II in biology and human health, the American Society for Biochemistry and Molecular Biology has hosted a biennial symposium on chromatin and RNA polymerase II since 2004. The 2018 symposium, titled “Transcriptional Regulation: Chromatin and RNA Polymerase II,” will be held in early October at the Snowbird Ski and Summer Resort, about 35 minutes from the Salt Lake City International Airport. The beautiful and intimate setting of the resort and the conference facilities provide extensive opportunities for scientific discussions and networking.

Attendance at the symposium will be capped at 200 participants, which will include principal investigators, postdoctoral fellows, students, and scientists from the pharmaceutical and biotech industries. Sessions will cover recent findings in RNA polymerase II regulation, including the contributions of noncoding RNAs, chromatin structure and post-translational modifications, and other factors that regulate gene expression. Dr. Eva Nogales of the University of California, Berkeley, will present the keynote address on her work on the structure and function of the RNA polymerase II transcriptional apparatus.

Students and postdoctoral fellows are encouraged to attend and will be eligible for poster awards; the winners will be given an opportunity to present their work as a short talk toward the end of the meeting. We look forward to seeing you in Snowbird for an exciting and enlightening symposium.

Transcriptional Regulation: Chromatin and RNA Polymerase II

Dates: Oct. 4—8
Location: Snowbird Ski and Summer Resort, Snowbird, Utah



Karen Arndt, University of Pittsburgh
Joseph Reese, Pennsylvania State University
Dylan Taatjes, University of Colorado–Boulder


Abstracts for platform presentations: March 16
Abstract submission for short oral presentations: July 19
Discounted registration: Aug. 14
Poster abstract submission: Aug. 30
Symposium registration: Sept. 12

The status of all submitted abstracts will be posted on the Meetings page.