JBC: Epigenetic function for extracellular Hsp90


In the Journal of Biological Chemistry, investigators at the Medical University of South Carolina report a new epigenetic function for extracellular heat shock protein 90 and describe a novel signaling pathway driving prostate cancer metastasis.

thumb nail

JBC: Small differences equal big results


Since the discovery of sphingolipids in the late 1800s, scientists have made a lot of progress in characterizing some of the diverse interactions and functions carried out by these often complex and enigmatic molecules. However, given the sheer number of these molecules, it seems likely that there are even more interactions waiting to be discovered. A Journal of Biological Chemistry thematic minireview series focuses on three structural variants, their functions and their intriguing therapeutic potential.

thumb nail

JBC: Researchers target Achilles' heel of MERS virus


In a paper published in the Journal of Biological Chemistry, researchers studying the viral enzyme nsp5, aka 3C-like protease, successfully blocked its function with inhibitor molecules. In the process, they also uncovered behavior that differentiates the enzyme from its counterpart in other coronaviruses.

thumb nail

JBC: Paul wins Tabor award


Bindu Paul won the Journal of Biological Chemistry/Herbert Tabor Young Investigator Award in May at the third European Conference on the Biology of Hydrogen Sulfide.

thumb nail

MCP: Better wine through better yeast hybrids


In a recent Molecular & Cellular Proteomics paper, researchers analyzed the molecular basis for heterosis in yeast, microorganisms on which the entire wine industry relies.

thumb nail

JLR: Super-fast spins hurt lipoproteins


Researchers in California decided to see how centrifuge speed affects high-density lipoproteins. 

thumb nail