The straight-jacket of hypothesis-driven research


ASBMB President Steven McKnight argues that "the NIH system of funding science is locked into the straight-jacket of hypothesis-driven research," which has "forced scientists to perform contractlike research that grant reviewers judge to be highly likely to succeed." 

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News from the Hill


Young scientists from colleges and universities across the United States arrived on Capitol Hill in June to meet with senators and representatives about the value of biomedical research. For a seventh year, the American Society for Biochemistry and Molecular Biology’s Hill Day gave young researchers the chance to talk with lawmakers and congressional staffers about the work they are doing.

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Member Update


Find out what's going on in the lives of your colleagues.

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Richard Nelson Perham (1937 – 2015)


Colleagues remember Richard Perham, who was distinguished for his work on the chemistry of proteins and the assembly of giant protein complexes.

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Lipids and lipid analogues as potential drugs


The biological activities of lipids underscore their potential for development as novel therapeutics. However, the broad roles of many lipids in diverse cellular processes also could detract from their clinical value because of undesired side reactions. In contrast, certain lipid biotransformation products have narrower spectrums of activities that could produce better-targeted drugs.

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All about ELISA


The enzyme-linked immunosorbent assay, better known as ELISA, exploits this antigen-antibody specificity to detect and measure, with the help of enzymes, the presence of proteins in samples of unknown composition and concentrations.

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Let’s talk about aphasia


Imagine life without language. For people living with aphasia, that’s their reality. Aphasia, which is caused by damage in the language centers of the brain, affects the ability to speak, understand speech, and read or write.

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Journal News


Catch up on recent publications in the Journal of Biological Chemistry, Molecular & Cellular Proteomics and the Journal of Lipid Research.

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A new name for the Institute of Medicine


The Institute of Medicine has been renamed the National Academy of Medicine. The name change comes as part of an internal reorganization at the National Academies.

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