JBC: Blindness and Parkinson’s disease


A research team has found a promising genetic link between blindness and Parkinson’s disease. This discovery, the researchers say, opens doors for new treatments of age-related disorders. The team’s study was published in the Journal of Biological Chemistry.

thumb nail

JBC: Jackie Corbin's scientific memoir


Viagra, Cialis and Levitra are all inhibitors of phosphodiesterase 5, an enzyme that breaks down cyclic guanosine monophosphate, which is important for increasing blood flow. The idea to use PDE5 inhibitors to promote blood flow came out of the work of Jackie Corbin, now an emeritus professor of molecular physiology and biophysics at Vanderbilt University.

thumb nail

JLR: Molecular insights for Niemann–Pick C disease


A recent thematic review in the Journal of Lipid Research summarizes the molecular mechanisms that underlie the lysosomal storage disease Niemann–Pick C and discusses the development of therapies for patients with this disorder.

thumb nail

MCP: Making mouse psoriasis relevant


A research group at Case Western Reserve University recently reported in the journal Molecular & Cellular Proteomics four proteins that are promising as drug targets for psoriasis.

thumb nail