Transcriptional regulation

Chromatin and RNA polymerase II

mountain landscape

Transcriptional Regulation: Chromatin and RNA Polymerase II
Oct. 2 – 6
Location: Snowbird Ski and Summer Resort, Snowbird, Utah
Organizers: Raymond Trievel, University of Michigan, and Joseph Reese, Pennsylvania State University

Raymond Trievel Joseph Reese
Trievel Reese

Early registration and abstract submission deadline:
Aug. 5

RNA polymerase II and chromatin are instrumental in regulating eukaryotic gene expression. A challenge to current research is to understand how RNA polymerase II coordinates messenger RNA synthesis and processing while contending with the formidable barrier of the nucleosome, resulting in proper cellular regulation and development. In light of the central importance of RNA polymerase II and chromatin in gene regulation, cellular development and the pathogenesis of human diseases, the American Society for Biochemistry and Molecular Biology is sponsoring this symposium.
The ASBMB has hosted this highly successful meeting on a biennial basis since 2004. Attendance is capped at 200 participants — principal investigators, postdoctoral fellows, students, and scientists from the pharmaceutical and biotech industries. The intimate setting provides extensive opportunities for interactions and networking between the participants.
The sessions will explore recent findings in transcriptional initiation, elongation and termination; co-transcriptional mRNA processing; and the role of RNA polymerase II in these processes. In addition, the contributions of chromatin structure, remodeling and covalent histone modifications in mediating gene regulation will be addressed.
Steven Henikoff of the Fred Hutchinson Cancer Center and the Howard Hughes Medical Institute will present the keynote lecture and will describe his research on nucleosome dynamics, chromatin remodeling and the functions of histone variants.
We look forward to seeing you at this exciting and enlightening symposium!