Detection and physiological role
|Photo courtesy of Donna Reid – Granlibakken Conference Center & Lodge
Translational Modifications: Detection and Physiological Role
Oct. 16 – 19
Location: Granlibakken Conference Center & Lodge, Tahoe City, Calif.
Organizers: Lauren Ball, Medical University of South Carolina, and Lance Wells, University of Georgia
Early registration and abstract submission deadline:
Post-translational modifications, or PTMs, create the enormous structural and functional diversity required to integrate information regarding the nutrient/stress status of the cell and regulate essential cellular functions. There are more than 400 known PTMs, and, almost without exception, virtually all polypeptides are post-translationally modified.
Recent technological advances, particularly in the area of mass spectrometry, are revealing new modifications and providing insights into the role of PTMs in integrating information and regulating signal transduction. This biannual meeting brings together leading experts in the study of a wide variety of different PTMs to allow cross-fertilization, presentation of the most exciting breakthroughs in the methodology and biological functions of PTMs, and lively discussions of new concepts and approaches.
Most of the talks will be selected from abstracts submitted by participants, allowing discussion of the most recent and exciting developments within the field. Natalie Ahn of the University of Colorado and the Howard Hughes Medical Institute will present the keynote lecture describing her research on the allosteric regulation of MAP kinase activity and new approaches aimed at revealing
mechanisms underlying cell polarity and directional movement.
This meeting not only will benefit newcomers to the field of PTMs but also will provide a forum for sharing breakthroughs in both methodology and biology for established investigators.