Post Translational Modifications: Detection and Physiological Evaluation
Drs. Katalin Medzihradszky and Gerald Hart
LOCATION: Granlibakken Conference Center and Lodge, Tahoe City, Calif.
DATE: Oct. 21 - Oct. 24, 2010
ORGANIZER: Katalin Medzihradszky, University of California, San Francisco
Gerald Hart, Johns Hopkins University School of Medicine
Aug. 15, 2010 -- Early Registration Deadline ($100 Savings) EXTENDED to August 27, 2010
Sept. 15, 2010 -- Abstract Submission Deadline and Registration Deadline
This meeting is supported through generous contributions by:
With the completion of the mapping of the human genome and rapid progress in understanding the proteome, it is now clear that the next phase of molecular bioscience research will by necessity largely focus on post-translational modifications (PTMs) and their regulation of protein functions. Currently, there are more than 400 known PTMs, and, almost without exception, virtually all polypeptides are post-translationally modified. Given the relatively small numbers of genes and polypeptides in complex organisms, PTMs create the enormous and highly dynamic structural and functional diversity required to regulate essential cellular functions.
In recent years, the technologies to quantitatively study PTMs at the molecular and structural levels have developed rapidly, particularly in the area of mass spectrometry. This biannual meeting brings together leading experts studying a wide variety of different PTMs to allow cross-fertilization, to house the presentation of the most exciting breakthroughs in the methodology and biological functions of PTMs, and to generate lively discussions of new concepts and approaches.
Based upon the enormous success of the first meeting held two years ago at Granlibakken, this meeting will not only benefit newcomers to the field of PTMs but also will provide a forum for sharing current breakthroughs in both methodology and biology to established investigators in the field.