Post Translational Modifications: Detection and Physiological Evaluation

Post Translational Banner 


Drs. Katalin Medzihradszky and Gerald Hart 

LOCATIONGranlibakken Conference Center and Lodge, Tahoe City, Calif.
DATE: Oct. 21 - Oct. 24, 2010

Katalin Medzihradszky, University of California, San Francisco
Gerald Hart, Johns Hopkins University School of Medicine

Aug. 15, 2010 -- Early Registration Deadline ($100 Savings) EXTENDED to August 27, 2010 
Sept. 15, 2010 -- Abstract Submission Deadline and Registration Deadline

Abstract Submission  RegisterButton  flier2  meeting article 
Meeting Housing  Meeting Program 

Questions? E-mail:








This meeting is supported through generous contributions by: 


  Agilent Technologies  Bruker Logo  Cell Signaling Technologies Inc.  Matrix Science  New Englad BioLabs  Thermo Fisher Scientific 



With the completion of the mapping of the human genome and rapid progress in understanding the proteome, it is now clear that the next phase of molecular bioscience research will by necessity largely focus on post-translational modifications (PTMs) and their regulation of protein functions. Currently, there are more than 400 known PTMs, and, almost without exception, virtually all polypeptides are post-translationally modified. Given the relatively small numbers of genes and polypeptides in complex organisms, PTMs create the enormous and highly dynamic structural and functional diversity required to regulate essential cellular functions. 

In recent years, the technologies to quantitatively study PTMs at the molecular and structural levels have developed rapidly, particularly in the area of mass spectrometry. This biannual meeting brings together leading experts studying a wide variety of different PTMs to allow cross-fertilization, to house the presentation of the most exciting breakthroughs in the methodology and biological functions of PTMs, and to generate lively discussions of new concepts and approaches. 

Based upon the enormous success of the first meeting held two years ago at Granlibakken, this meeting will not only benefit newcomers to the field of PTMs but also will provide a forum for sharing current breakthroughs in both methodology and biology to established investigators in the field.