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JBC Thematic Minireview Series - Metals in Biology 2014

September 2, 2014 — This thematic series addresses the issue of why certain metals are used by particular enzymes, as well as the consequences of using the wrong metal. The first Minireview in the series deals with general aspects of metal specificity, and the next two deal with specific cases, the enzyme ribonucleotide reductase and iron/manganese homeostasis in the bacterium Bacillus subtilis. The fourth discusses with metal selection in oxidative stress, and the final organelles (lysomes) as mediators of metal homeostasis.

Read all of the articles in this series here  

JBC Thematic Review Series: Phospholipase D and Cancer

Phospholipase D JBC Cover w shadow
Phospholipase D signaling plays a critical role in cell growth and proliferation, vesicular trafficking, secretion and endocytosis. Cancer invasion and metastasis rely heavily on cellular motility, and, as such, they have put PLD at center stage in cancer research, as outlined in this Journal of Biological Chemistry minireview series organized by Julian Gomez-Cambronero and George M. Carman.

 

JBC Thematic Minireview Series - Inteins

May 23, 2014 — Intein-mediated protein splicing raises questions and creates opportunities in fields that range from evolutionary biology, enzymology and molecular biophysics to protein design and biotechnology, as outlined in this minireview series.

Read all of the articles in this minireview series here.



JBC Thematic Minireview Series - Prions

May 23, 2014 — Prions are self-replicating protein aggregates and are the primary causative factor in a number of neurological diseases in mammals. The minireviews in this thematic series highlight the recent advances in prion biology and the role these unique proteins play in disease.

Read all of the articles in this series here

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