JBC Thematic Minireview Series - Molecular Basis of Selection of Metals by Enzymes

July 26, 2016 — This ninth Metals in Biology Thematic Series deals with the fundamental issue of why certain enzymes prefer individual metals. Why do some prefer sodium and some potassium? Is it just the size? Why does calcium have so many regulatory functions? Why do some proteins have an affinity for zinc? How is the homeostasis of calcium and zinc achieved? How do enzymes discriminate between the similar metals magnesium and manganese? Four Minireviews address these and related questions about metal ion preferences in biological systems.

Read all of the articles in this series here

JBC Thematic Minireview Series - Biofilms

April 21, 2016 — The biofilms that many bacteria and fungi produce enable them to form communities, adhere tightly to surfaces, evade host immunity, and resist antibiotics. Pathogenic micro-organisms that form biofilms are very difficult to eradicate and thus are a frequent source of life threatening, hospital acquired infections. This series of five minireviews from the Journal of Biological Chemistry provides a broad overview of our current understanding of biofilms and the challenges that remain.

Read all of the articles in this series here

JBC Thematic Minireview Series - Cell Signaling in Simple Organisms

April 8, 2016 — All cells discriminate environmental signals and generate appropriate intracellular responses. Our understanding of these signal transduction mechanisms has benefitted from studies across the kingdoms of life, from fungi and fish to mice and men. This thematic mini-review series examines lessons learned from three of the simplest (and best understood) eukaryotic model organisms.

Read all of the articles in this series here

Journal of Biological Chemistry names new editor in chief

LilaThe American Society for Biochemistry and Molecular Biology announced Tuesday that Lila M. Gierasch, a distinguished faculty member at the University of Massachusetts Amherst, will be the next editor in chief of the Journal of Biological Chemistry, the nonprofit’s peer-reviewed journal. Gierasch’s five-year term will begin July 1. She will take the reins from the journal's interim editor, F. Peter Guengerich, a researcher at Vanderbilt University and longtime associate editor who has steered the highly cited journal since July 2015.

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