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New JBC Podcast: vitmain C’s potential role in epigenetics — an interview with Geofeng Wang

Gaofeng WangMay 10, 2013 — In the latest JBC podcast, we hear an interview with Gaofeng Wang at the University of Miami. Wang talks about his Paper of the Week: Ascorbate Induces Ten-Eleven Translocation Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine. The paper delves into how vitamin C may play a role in epigenetics. Click here to listen to the podcast. 

LSUHSC research discovers new drug target for metastatic breast cancer

NischApril 15, 2013 — Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the growth and spread of breast tumor cells to the lungs. The research was published last week online in The Journal of Biological Chemistry. More...

LSUHSC research reveals RX target for HPV, HEP C and related cancers

UBE3AApril 15, 2013 — New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to “rewire” themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer. The research was published in the April 12, 2013, issue of The Journal of Biological Chemistry. More...

Secrets of bacterial slime revealed

SinRApril 15, 2013 – Newcastle University scientists have revealed the mechanism that causes a slime to form, making bacteria hard to shift and resistant to antibiotics. When under threat, some bacteria can shield themselves in a slimy protective layer, known as a biofilm. It is made up of communities of bacteria held together to protect themselves from attack. Publishing in The Journal of Biological Chemistry, the team reveal how a molecular switch regulates biofilm formation. This new understanding could help identify a new target for antibiotics and prevent other biofilms from forming. More...

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