Ruedi Aebersold is the recipient of the Herbert A. Sober Lectureship

AbersoldRuedi Aebersold, a pioneer in the field of proteomics who holds a joint appointment as professor of molecular systems biology at ETH-Zürich and the University of Zürich, has been named the recipient of the Herbert A. Sober Lectureship.

His nominators point to his development of a series of methods that have found wide application in analytical protein chemistry and proteomics, like a new class of reagents used in quantitative mass spectrometry termed “isotope-coded affinity tag,” or ICAT, reagents.

“(Aebersold) uses the protein profiles determined by this method to differentiate cells in different states, such as noncancerous versus cancerous cells, and to systematically study how cells respond to external stimuli,” explained Fuchu He, president and director of the Beijing Proteome Research Center and director of the China National Center of Biomedical Analysis. “These ‘snapshot’ profiles indicate which cells contain abnormal levels of certain proteins. This is expected to lead to new diagnostic markers for disease and to a more complete understanding of the biochemical processes that control and constitute cell physiology.”

He underscored that the methods Aebersold developed are now used in thousands of laboratories around the world and are contributing to an explosion of new biological and clinical knowledge.

“The series of his contributions has fueled the proteomic revolution,” He said.

Aebersold, the founding chairman of the Institute of Molecular Systems Biology and also an associate editor at the ASBMB journal Molecular and Cellular Proteomics, has received the American Society for Mass Spectrometry Biemann Medal, the Pehr Edman Award, the Widmer Award, the World Technology Network Award for Biotechnology, the Genome Technology Award in proteomics in two consecutive years and the Human Proteome Organization achievement award, among others.

“He has inspired a whole generation of young scientists at the University of Washington, the Institute for Systems Biology, and the ETH-Zurich, as well as indirectly through his publications and his active engagement in many leading professional organizations,” wrote Gilbert S. Omenn, professor of internal medicine, human genetics and public health at the University of Michigan Medical School and vice president of the Human Proteome Organization.

The Herbert A. Sober Lectureship recognizes outstanding biochemical and molecular biological research, with particular emphasis on development of methods and techniques to aid in research.  The winner receives a plaque, $3,000 and transportation and expenses to present a lecture at the 2010 ASBMB Annual Meeting.

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