Protein Synthesis, Catalysis and Turnover Theme
Theme Organizers:
Terri Goss Kinzy, UMDNJ Robert Wood Johnson Medical School and
Zhen-Qiang Pan, Mount Sinai School of Medicine
Short talks for this theme will be selected from the volunteered abstracts.
(* denotes Session Chair)
Protein Synthesis: Mechanism and Regulation
Sunday, April 25
3:30 PM - 5:50 PM, Room 304B
David M. Bedwell*, University of Alabama at Birmingham
Thomas Dever, NIH
Molecular Genetic Dissection of Translation
Terri Goss Kinzy, UMDNJ Robert Wood Johnson Medical School
Mechanism and regulation of translation elongation
Marina Rodrina, Max Planck Institute for Biophysical Chemistry
Quality Control Mechanisms in Protein Synthesis
Protein Synthesis: Translation in Medicine
Monday, April 26
9:55 AM - 12:15 PM, Room 304B
Terri Goss Kinzy*, UMDNJ Robert Wood Johnson Medical School
David M. Bedwell, University of Alabama at Birmingham
Pharmacological Suppression of Nonsense Mutations to Treat Genetic Diseases
Estela Jacinto, UMDNJ Robert Wood Johnson Medical School
mTOR signaling in translation and folding
Robert J. Schneider, New York University Cancer Institute
Translational regulation in breast cancer
Protein Turnover: Tagging Substrates for Ubiquitination
Tuesday, April 27
3:30 PM - 5:50 PM, 304B
Zhen-Qiang Pan*, Mount Sinai School of Medicine
Mechanistic insights into substrate polyubiquitination
Vishva Dixit, Genentech, Inc.
Deubiquitinases as regulators of cellular signaling
Dieter Wolf, Universität Stuttgart
The Ubiquitin-Proteasome System in Protein Quality Control and the Disposal of Protein Waste
Thematic Reception
Tuesday, April 27
5:50 PM - 6:30 PM, Third Floor Foyer
Join us immediately following, "Protein Turnover: Tagging Substrates for Ubiquitination
Protein Turnover: Function and Regulation of the 26S Proteasome
Wednesday, April 28
9:45 AM - 12:05 PM, Room 304B
Ivan Dikic*, Goethe University School of Medicine
Targeting ubiquitin networks
David Glass, Novartis Institute for Biomedical Research
Signaling pathways that perturb skeletal muscle atrophy and hypertrophy
David Fushman, University of Maryland, College Park
Structural insights into polyubiquitin signal recognition by the proteasome