Protein Synthesis, Catalysis and Turnover Theme

Theme Organizers:
Terri Goss Kinzy, UMDNJ Robert Wood Johnson Medical School and
Zhen-Qiang Pan, Mount Sinai School of Medicine

Short talks for this theme will be selected from the volunteered abstracts.

(* denotes Session Chair)

Protein Synthesis: Mechanism and Regulation
Sunday, April 25
3:30 PM - 5:50 PM, Room 304B

David M. Bedwell*, University of Alabama at Birmingham

Thomas Dever, NIH
Molecular Genetic Dissection of Translation

Terri Goss Kinzy, UMDNJ Robert Wood Johnson Medical School
Mechanism and regulation of translation elongation

Marina Rodrina, Max Planck Institute for Biophysical Chemistry
Quality Control Mechanisms in Protein Synthesis   

Protein Synthesis: Translation in Medicine
Monday, April 26
9:55 AM - 12:15 PM, Room 304B

Terri Goss Kinzy*, UMDNJ Robert Wood Johnson Medical School

David M. Bedwell, University of Alabama at Birmingham
Pharmacological Suppression of Nonsense Mutations to Treat Genetic Diseases

Estela Jacinto, UMDNJ Robert Wood Johnson Medical School
mTOR signaling in translation and folding

Robert J. Schneider, New York University Cancer Institute
Translational regulation in breast cancer

Protein Turnover: Tagging Substrates for Ubiquitination             
Tuesday, April 27
3:30 PM - 5:50 PM, 304B

Zhen-Qiang Pan*, Mount Sinai School of Medicine
Mechanistic insights into substrate polyubiquitination

Vishva Dixit, Genentech, Inc.
Deubiquitinases as regulators of cellular signaling

Dieter Wolf, Universität Stuttgart
The Ubiquitin-Proteasome System in Protein Quality Control and the Disposal of Protein Waste

Thematic Reception
Tuesday, April 27
5:50 PM - 6:30 PM, Third Floor Foyer
Join us immediately following, "Protein Turnover: Tagging Substrates for Ubiquitination

Protein Turnover: Function and Regulation of the 26S Proteasome
Wednesday, April 28
9:45 AM - 12:05 PM, Room 304B

Ivan Dikic*, Goethe University School of Medicine
Targeting ubiquitin networks

David Glass
, Novartis Institute for Biomedical Research
Signaling pathways that perturb skeletal muscle atrophy and hypertrophy

David Fushman, University of Maryland, College Park
Structural insights into polyubiquitin signal recognition by the proteasome



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