DNA Transactions Theme

Theme Organizers:
Ellen H. Fanning, Vanderbilt University and
Thomas A. Kunel, NIEHS, NIH

Short talks for this theme will be selected from the volunteered abstracts.

(* denotes Session Chair)

DNA Synthesis and Mutagenesis
Sunday, April 25
9:55 AM - 12:15 PM, Room 304A

Ellen H. Fanning*, Vanderbilt University

Thomas A. Kunkel, NIEHS, NIH
Eukaryotic DNA replication fidelity

Helle D. Ulrich, Cancer Research UK
Timing and spacing of ubiquitin-dependent DNA damage bypass

Graham C. Walker, Massachusetts Institute of Technology
Function and control of translesion synthesis polymerases

Replication Fork Dynamics
Monday, April 26
3:30 PM - 5:50 PM, Room 304A

Graham C. Walker*, Massachusetts Institute of Technology

James M. Berger, University of California, Berkeley
Structural mechanisms for initiating DNA replication

Ellen H. Fanning, Vanderbilt University
Molecular hand-off in viral DNA replication

James L. Keck, University of Wisconsin, Madison
Structural mechanisms of bacterial replication

Thematic Reception
Monday, April 26
5:50 PM - 6:30 PM, Third Floor Foyer
Join us immediately following, "Replication Fork Dynamics."

DNA Damage Signaling and Repair
Tuesday, April 27
9:55 AM - 12:15 PM, Room 304A

Helle D. Ulrich
*, Cancer Research UK

David Cortez, Vanderbilt University School of Medicine
Genome maintenance by the DNA damage response

Nicole J. Francis, Harvard University
Mechanisms of Epigenetic Inheritance through DNA Replication

W. Matthew Michael, Harvard University
Regulated proteolysis of a translesion DNA polymerase on DNA

The 3Rs, Genome Instability, and Disease
Wednesday, April 28
1:30 PM - 3:50PM, Room 304A

Thomas A. Kunkel*, NIEHS, NIH

William C. Copeland, NIEHS, NIH
Defects in mitochondrial DNA replication and human disease

Penelope A. Jeggo, University of Sussex
The influence of higher order chromatin structure on genomic instability and human disease

Cynthia T. McMurray, Mayo Clinic, Rochester
DNA Repair gone wrong: mechanisms of trinucleotide expansion



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