DNA Transactions Theme
Theme Organizers:
Ellen H. Fanning, Vanderbilt University and
Thomas A. Kunel, NIEHS, NIH
Short talks for this theme will be selected from the volunteered abstracts.
(* denotes Session Chair)
DNA Synthesis and Mutagenesis
Sunday, April 25
9:55 AM - 12:15 PM, Room 304A
Ellen H. Fanning*, Vanderbilt University
Thomas A. Kunkel, NIEHS, NIH
Eukaryotic DNA replication fidelity
Helle D. Ulrich, Cancer Research UK
Timing and spacing of ubiquitin-dependent DNA damage bypass
Graham C. Walker, Massachusetts Institute of Technology
Function and control of translesion synthesis polymerases
Replication Fork Dynamics
Monday, April 26
3:30 PM - 5:50 PM, Room 304A
Graham C. Walker*, Massachusetts Institute of Technology
James M. Berger, University of California, Berkeley
Structural mechanisms for initiating DNA replication
Ellen H. Fanning, Vanderbilt University
Molecular hand-off in viral DNA replication
James L. Keck, University of Wisconsin, Madison
Structural mechanisms of bacterial replication
Thematic Reception
Monday, April 26
5:50 PM - 6:30 PM, Third Floor Foyer
Join us immediately following, "Replication Fork Dynamics."
DNA Damage Signaling and Repair
Tuesday, April 27
9:55 AM - 12:15 PM, Room 304A
Helle D. Ulrich*, Cancer Research UK
David Cortez, Vanderbilt University School of Medicine
Genome maintenance by the DNA damage response
Nicole J. Francis, Harvard University
Mechanisms of Epigenetic Inheritance through DNA Replication
W. Matthew Michael, Harvard University
Regulated proteolysis of a translesion DNA polymerase on DNA
The 3Rs, Genome Instability, and Disease
Wednesday, April 28
1:30 PM - 3:50PM, Room 304A
Thomas A. Kunkel*, NIEHS, NIH
William C. Copeland, NIEHS, NIH
Defects in mitochondrial DNA replication and human disease
Penelope A. Jeggo, University of Sussex
The influence of higher order chromatin structure on genomic instability and human disease
Cynthia T. McMurray, Mayo Clinic, Rochester
DNA Repair gone wrong: mechanisms of trinucleotide expansion