Biological Chemistry of RNA Theme

Theme Organizers:
Martha J. Fedor, The Scripps Research Institute and
Sarah A. Woodson, Johns Hopkins University

Short talks for this theme will be selected from the volunteered abstracts.

(* denotes Session Chair)



Post-transcriptional Gene Regulation
Sunday, April 25
9:55 AM - 12:15 PM, Room 304B

Melissa J. Moore*, HHMI/University of Massachusetts Medical School
mRNAs with a complex: The long-term consequences of a nuclear upbringing

Jeffrey S. Kieft, University of Colorado, Denver School of Medicine
Structural Mimicry at the Heart of Translation Initiation by a Viral IRES

Kimberly Mowry, Brown University
RNA transport in the cytoplasm: How to get there from here



Ribosome Assembly and Function
Monday, April 26
3:30 PM - 5:50 PM, Room 304 B

Sarah A. Woodson*, Johns Hopkins University
RNA folding during assembly of the 30S ribosome

Harry Noller, University of California, Santa Cruz               
Structure and dynamics of the ribosome              

Jamie R. Williamson, The Scripps Research Institute
Cellular physiology of bacterial ribosome assembly



Thematic Reception
Monday, April 26
5:50 - 6:30 PM, Third Floor Foyer 
Join us immediately following the conclusion of, "Ribosome Assembly and Function."




Splicing Mechanism and Regulation
Tuesday, April 27
9:55 AM - 12:15 PM, Room 304B

Douglas L. Black*, HHMI/University of California, Los Angeles
Alternative splicing and the regulation of neuronal gene expression

Magda Konarska, Rockefeller University
Spliceosome dynamics and their impact on the fidelity of splice site selection

Jonathan P. Staley, University of Chicago
Constraining errors in splice site choice



Ribozyme Structure and Function
Wednesday, April 28
1:30 PM - 3:50 PM, Room 304B

Martha J. Fedor*, The Scripps Research Institute
Active site purines and catalysis of RNA self-cleavage

Dipankar Sen, Simon Fraser University, Canada
Towards thiamine-utilizing ribozymes

Hiroaki Suga, University of Tokyo
Structure and catalysis of flexizymes, flexible tRNA acylation ribozymes, and their technical potentials


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