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2015 ASBMB MEETING LIPID THEME
Lipids - In Vivo Dynamics, Protein Partners, and Signaling
March 29, 2015 – April 1, 2015, Boston, MA

This year marks the 42th anniversary of the publication of the fluid mosaic model of cell membranes by Singer and Nicholson. While it was a seminal paper in the lipid field, the authors did make one unfortunate mistake by depicting lipids as “bland” molecules, serving primarily as a passive barrier and a host for membrane proteins, an idea that has been adopted by many standard biochemistry textbooks. Much has changed since then and now it is hard to find any area of biology where lipids do not play “crucial” regulatory roles. The critical roles of lipids are ever expanding to many unsuspected areas, and that is the topic of our first session: Multi-Talented Lipids.

Recent advances in chemical biology and molecular imaging technologies have allowed researchers to identify new lipid-binding proteins, specifically manipulate diverse lipid signaling, and directly monitor lipid dynamics and lipid-mediated cellular activities with high spatiotemporal resolution. These exciting new developments will be covered in two sessions, Lipids Meet Chemistry and Lipids Caught in Action, as well as a workshop, Chemical and Optogenetic Manipulation of Lipid Signaling.

With all this functional information, the time is ripe for mechanistic investigation on how lipids can perform such diverse regulatory roles, with a special emphasis on how lipids regulate the structure and function of their effector proteins. In the final session (Lipid Magic: How Do They Do it?), we will witness how state-of-art structural and analytical tools have led to mind-boggling new discoveries that answer this important question. Overall, these sessions will not only present new functional information on lipids and new technologies to study lipids but also help change the way both experts and non-experts think about and study lipid-mediated cellular processes. Everyone is invited to this lipid celebration.

 Click Here for more information regarding Lipid themed meetings at the ASBMB 2015 Annual Meeting in Boston, MA

The abstract submission site is now open and accepting abstracts for the meeting http://www.asbmb.org/meetings/annualmeeting2015/abstracts/instructions/ Volunteered abstract submission deadline is THURSDAY, NOVEMBER 6, 2014 Abstracts should be submitted using ASBMB Abstract Topic Categories # 2140-2170

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SCIENTIFIC SESSIONS:
- PGE2 in PATHOPHYSIOLOGY
- PROSTANOIDS and the CARDIOVASCULAR SYSTEM
- NOVEL LIPID MEDIATORS AND ADVANCES IN LIPID MEDIATOR ANALYTICS
- LIPOXYGENASES
- ADIPOSE TISSUE and BIOACTIVE LIPIDS

See the PROGRAM in detail.

We especially welcome graduate and postdoctoral students to attend this workshop, and a special session (Young SESSION + travel award) will be devoted to them.

In addition, abstracts for posters can be submitted online, and 20 additional oral communications will be selected from the submitted abstracts.

The registration fee is 250 euros (50 euros for students or post-docs).

Feel free to go on our website for on-line information, registration and abstract submission.

 

 

 

 

 

From Protein Trafficking to Lipid Sorting: A Fascinating Lipid Journey

In the newest “Lipid News” article, Fred Maxfield discusses how he became interested in lipid trafficking that eventually led him to some seminal discoveries. As Fred notes in his article “Basic mechanisms for maintaining distinct lipid compositions in different organelles are only partially understood, which means that this is an area where fundamental principles are still awaiting discovery”. And much was discovered. This article outlines Fred’s discovery of lipid sorting and trafficking using a variety of state-of-the-art techniques. It’s a wonderful story that highlights discovery that arises from the interdisciplinary approaches of cell biology biochemistry and biophysics of membranes. It’s a fun read and one that captures the excitement of graduate student that still lives in an established investigator.

See the full article

 

LIPID NEWS: Desperately seeking Sputnik for fundamental science

It is clear that researchers and the public need something around which they can rally, but what should it be?

 

 

Congratulations to the new Lipid Division Award winners!

This year’s Shaw Young Investigator in Lipid Research Award Winner is Mary L. Kraft at the University of Illinois at Urbana-Champaign. Dr. Kraft’s research focuses on using mass spectrometry to image lipids in cellular systems. She has developed and applied new and important methodologies to assess the organization of cholesterol and sphingolipids in the plasma membrane. 

View meeting Lecture

 

This year’s Avanti Award in Lipids Winner is Sandra L. Hofmann at the University of Texas Southwestern Medical Center at Dallas. Dr. Hofmann’s research focuses on the metabolism of proteins modified by lipids. This work has lead to a better understanding of how mutations in the palmitoyl protein thioesterase gene contribute to a group of hereditary brain disorders called the neuronal ceroid lipofuscinoses.

View meeting Lecture

 

Check out the new thematic series on Fat-Soluble Vitamins in the Journal of Lipid Research. This series is introduced by Mary L. Chang ASBMB Publications Manager for the Journal of Lipid Research in the August issue of ASBMB today:

Vitamins A, D, E and K are the four fat-soluble vitamins required to maintain good health in higher organisms. The July issue of the Journal of Lipid Research marks the beginning of a thematic series on these vitaminscoordinated by editorial board member William S. Blaner of Columbia University. The special section in the July issue includes an introductory editorial by Blaner and four reviews from experts on vitamin A. Subsequent issues this year will explore vitamins D, E and K.

In developing countries, vitamin A deficiency remains a major public health concern, and much research is focused on identifying populations most at risk. Coordinated efforts in molecular research to develop vitamin-A–fortified plant sources could help eradicate this public health problem. Epidemiologic studies are being conducted to understand how dietary intake of the vitamin might be related to development or incidence of certain diseases. The four thematic reviews in July’s JLR focus on vitamin A’s molecular actions and its metabolism.

In one review, Abdulkerim Eroğlu and Earl H. Harrison of Ohio State of University explore the research insights on carotenoid conversion to vitamin A, carotenoid metabolism to create apo-carotenoids, and the actions and metabolism of carotenoids in higher animals.

Columbia University’s Sheila M. O’Byrne and William S. Blaner’s contribution to the series examines how vitamin A is stored in the body as retinyl esters, how they evolved, and how mobilization of these stores is achieved through the actions of specific vitamin-A–binding proteins and enzymes.

Natalia Y. Kedishvili of University of Alabama at Birmingham reviews what is known of the formation of retinoic acid and how it is broken down and eliminated from cells and tissues.

In the fourth and final review, Ziad Al Tanoury, Aleksandr Piskunov and Cecile Rochette-Egly of France’s Institut de Génétique et de Biologie Moléculaire et Cellulaire discuss what is known about the retinoic acid receptors, how retinoic acid can affect genomic expression and the nongenomic effects of vitamin A.

 

ASBMB science writer Raj Mukhopadhyay has written some fascinating lipid-related blog posts. Check out one of the latest posts showcasing research indicating that gut bacteria may be a source of male steroid hormones. There are many more fascinating posts to browse on her blog Wild Types!

  

UP COMING LIPID MEETINGS

Kern Lipid Conference

Evolving Concepts of HDL Function in Cardiomeabolic Diseases and Beyond
Vail, Colorado
http://www.kernconference.org

 
ISPL 2014

21st International Symposium on Plant Lipids
Guelph, Canada - July 6-11, 2014
https://www.uoguelph.ca/ispl2014/

 
12th Euro Fed Lipid Congress

"Oils, Fats and Lipids: From Lipidomics to Industrial Innovation"
14-17 September 2014, Montpellier, France
http://www.eurofedlipid.org/meetings/montpellier2014/index.php

 
Systems Biology of Lipid Metabolism (B4)

Scientific Organizers: Matej Orešič, Antonio J. Vidal-Puig and Ana Maria Cuervo
February 9—13, 2015
Beaver Run Resort, Breckenridge, Colorado, USA
http://www.keystonesymposia.org/15B4

 
FASEB Science Research Conferences

Molecular Mechanisms of Intestinal Lipid Transport & Metabolism
July 6-11, 2014
Snowmass, Colorado
http://www.faseb.org/src

 

 

in the spotlight

  

 

JOB BOARD