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Lipid job series: lipidomic method development

5/17/2019 2:29:28 PM

As we previously highlighted on the careers blog, metabolomics refers to profiling the small molecules (or metabolites) present within biological samples. One class of analyzed metabolites are lipids. (The corresponding -omics studies are referred to collectively as lipidomics, and a collection of lipid species in a sample is called the lipidome.) In general, quantitative lipid measurements employ some type of mass-spectrometry technique. With technological advances in MS instrumentation, lipidomic analysis is becoming more accessible to any research lab. To learn more about the latest trends in lipidomics, you can browse through the methods papers in the Journal of Lipid Research. Another useful website to check out is the Lipid MAPS Lipidomics Gateway, which provides open access to a large number of lipidomics resources (e.g., structure database, protocols). While much progress has been made in measuring lipids, more work is still needed to standardize methodologies and reference samples, as underscored in this recent ASBMB Today article on harmonizing lipidomics. So, for this week, we feature science jobs related to method development in lipidomics.  

Weekly jobs roundup  

  • Thermo Fisher Scientific has several open positions related to lipid analysis. These include an analytical chemistry R&D scientist in lipidomics/lipid biomarkers (Waltham, Mass.) and a validation scientist in the chromatography and mass spectrometry division (San Jose, Calif.). Both positions require significant experience with LC-MS methodologies and instrumentation. No application deadlines are provided.  
  • Synthetic Genomics (La Jolla, Calif.) is recruiting a metabolomics scientist to develop analytical methods for metabolite profiling and measurements of small molecules such as lipids. Minimum qualifications include a Ph.D. in analytical chemistry, biochemistry, physical chemistry or other relevant discipline. Preference is for candidates who are experienced in analyzing diverse types of biological materials (e.g., phototrophic systems) and within the context of metabolic engineering. No application deadline is provided.  
  • The Mass Spectrometry Center in the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy has two openings for mass-spectrometry specialists. Priority areas of expertise include metabolomics and quantitative mass spectrometry. Both positions require a bachelor’s degree in chemistry or a related field and varying levels of experience depending on the job rank. See the posting for more details. No application deadline is provided.  
  • Metabolon (Research Triangle Park, N.C.), a metabolomics diagnostic products and services company, has multiple openings across its contract services division that include sample preparation, data curation and quality assurance. Additionally, the company is hiring business development executives to promote its metabolomic and lipidomic services in the Boston and southern California markets. See the job board for a full listing of open positions. No application deadlines are provided.  
  • The Joint BioEnergy Institute (Emeryville, Calif.) at Lawrence Berkeley National Laboratory is hiring a research associate to run mass spectrometry-based analytical methodologies for metabolite analysis, contribute to method development and support metabolic-engineering experiments. Desired qualifications include a bachelor’s degree in chemistry, biochemistry, molecular biology, microbiology or a related field and up to two years of related experience. No application deadline is provided.  

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Donna Kridelbaugh is a contributor to the ASBMB Careers Blog. She holds an advanced degree in microbiology and is a former lab manager.   

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