Epigenomics and epigenetics research jobs

3/18/2019 3:55:08 PM

The ASBMB is hosting a scientific symposium titled Evolution and Core Processes in Gene Expression from May 9–12 at Michigan State University. The meeting will highlight research trends in gene expression and evolution, which includes invited talks in the subdisciplines of developmental and evolutionary epigenetics.  

We have seen quite a few epigenomics and epigenetics-related jobs posted lately, so we wanted to delve more into this topic here on the careers blog. Epigenomics is a growing field dedicated to understanding how epigenetic changes, either by direct chemical modification of DNA or post-translational modifications to histone proteins (which subsequently impacts chromatin structure), affect gene-expression profiles. The collection of epigenetic changes in a cell or an entire organism is referred to as the epigenome.  

Overall, the epigenome is essential for normal cell development and programming. But, other factors (e.g., exposure to environmental toxins) can alter the epigenome and deregulate critical cell processes, possibly leading to the onset of many diseases (e.g., cancer, diabetes). These epigenetic changes also may be inherited by future generations.  

There are many research opportunities to get involved with studying the basic mechanisms of epigenetic processes and how this translates into biomedical applications. This week, we feature a selection of epigenetics-research jobs for bachelor’s to Ph.D.-degree holders. These jobs were found by searching through social-media feeds and on the International Human Epigenome Consortium job board.  

Weekly jobs roundup  

  • The laboratory of Capucine Van Rechem in the Department of Pathology at Stanford University is hiring both a life science technician and postdoctoral researcher. The lab studies the role of chromatin modifiers, particularly how histone and DNA modifications influence cellular processes (e.g., transcription, replication, genomic stability and cell division), during disease progression such as with cancer. See the postings for more details. (H/t to Lívia Uličná who shared both of these opportunities on Twitter. Lívia also points out that the technician position is a good fit for any recent graduates who want to gain more experience before applying to graduate school.)  
  • The laboratory of Danesh Moazed at Harvard Medical School is seeking a laboratory manager to join the group. The lab researches the assembly and epigenetic inheritance of chromatin silent domains in yeast and mammalian model organisms. Minimum qualifications include a bachelor’s degree in biochemistry, biology or a related field and experience with molecular biology and biochemistry techniques. The hiring is being done through the Howard Hughes Medical Institute. See the job posting for instructions on how to apply.  
  • EpiCypher (Research Triangle Park, N.C.), a bioscience company that provides tools and services for epigenetics and chromatin-biology research, is hiring for multiple positions that include two research associates and a research scientist. They also offer a two-year postdoc fellowship option that can be established with a North Carolina-based university lab to work on a project of commercial interest to the company. Check out the section on academic programs on the website for more info about this program.  
  • The Sidoli Lab at the Albert Einstein College of Medicine (New York City) has two openings for postdoctoral researchers. This is a newly established proteomics laboratory that studies chromatin dynamics, complex assembly on chromatin and new epigenetics targets for disease therapy. See the lab’s website for more details about ongoing research projects.  

Editor’s note  

There is still time to make plans to attend and present at the ASBMB Evolution and Core Processes in Gene Expression symposium. The oral programming abstract deadline has been extended to March 24 and both the poster programming abstract and registration deadlines to April 4. (Note: There is a discounted registration fee if you sign up by March 28.) Check out the symposium website for more information.  

Also, the ASBMB is partnering with the Biophysical Society of China to present a symposium titled Interplay Between Epigenetic Regulation and Genome Integrity from Oct. 20–24 in Beijing. Registration for this five-day symposium opens April 1. The abstract deadline is Aug. 30. Here’s the meeting website.

Donna Kridelbaugh is a contributor to the ASBMB Careers Blog. She holds an advanced degree in microbiology and is a former lab manager.   

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