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Beat the holiday stress with these research jobs

12/14/2018 4:47:30 PM

The rush of the winter-holiday season is upon us with so much hustling to finish grading those final exam papers, to set up one more last-minute experiment before heading home for break, and to find that perfect gift for your lab mates (see the author’s note for some help there). And, all this rushing can cause a lot of stress. (Are you feeling it yet? Yeah, me too.)  

While small doses of stress can have some short-term, positive effects, chronic stress takes a toll on your body (e.g., high blood pressure, weight gain) and may lead to unhealthy lifestyle choices (one more cookie will make it all better, right?). So, this winter break, be sure to take some time to unplug and relax, set realistic goals for any professional work you want to accomplish during this time, and know that it’s OK to just take a break.  

At the cellular level, we experience stress as well, which can disrupt metabolism and other vital processes. For example, sleep disturbances and high-sugar diets may make cells more susceptible to oxidative stress. This refers to an imbalance in the ratio of oxidants to antioxidants. During normal cellular processes (e.g., aerobic respiration in mitochondria), reactive oxygen species are produced, but too many ROS wreaks havoc on the macromolecules in your cells. In fact, oxidative stress has been associated with a wide range of diseases, including cancer, cardiovascular disease, diabetes and neurodegenerative disorders.    

To help alleviate some of your job-hunting stress this week, we bring you roundup of jobs related to cellular stress research. Some keywords for future job searches in this area may include reactive oxygen species; redox signaling; cellular, metabolic or oxidative stress; and stress-signaling pathways.  

Weekly jobs roundup  

  • The Aging Institute at the University of Pittsburgh is seeking a research specialist to conduct independent research in the areas of stress response, organelle biology, metabolism and drug discovery. Minimum qualifications include a bachelor’s degree in biology, biochemistry or a related field and one to two years of relevant experience. No application deadline is provided.  
  • The Health Disparities Research Section of the Laboratory of Epidemiology and Population Science at the NIH’s National Institute on Aging has an opening for a postdoctoral research fellow. The lab examines the molecular biology of health disparities, aging and age-related diseases, with a focus on inflammation and oxidative stress in chronic disease. Candidates with a background in mitochondrial biology and oxidative stress are especially encouraged to apply. Applicants must have less than five years of postdoc experience to be eligible. The application deadline is Dec. 31.  
  • The NIH’s National Center for Advancing Translational Sciences (Rockville, Md.) is hiring a research biologist to work on the development of disease-relevant screening assays to validate biological targets and for drug development. The posting states that areas of special interest include cell stress, neuroscience, oncology and target-engagement assays. Minimum qualifications include a Ph.D. in cell biology, molecular biology, pharmacology or a related discipline and at least two years of postgraduate experience. No application deadline is provided.  
  • The Department of Neurology Research at Massachusetts General Hospital (Boston) is hiring a research scientist (job number 3080017) to work as part of the Interdisciplinary Brain Center, Alzheimer’s Clinical and Translational Research Unit and the MGH Institute for Neurodegenerative Diseases. The incumbent will develop and validate biofluid biomarker assays for the diagnosis of and monitoring drug-treatment response related to neurodegenerative diseases, which includes biomarkers for pathophysiological indicators (e.g., oxidative stress). Minimum qualifications include a Ph.D. or M.D. with neurosciences training and five years of related experience. No application deadline is provided.  
  • The Hou Laboratory at Thomas Jefferson University has postdoctoral research openings in the area of RNA research. Specifically, projects will focus on: 1) how epigenetic posttranscriptional modifications of tRNA regulates gene expression in neurodegenerative diseases; and 2) codon-specific translation in response to stress. See the lab website for instructions on how to apply. No application deadlines are provided.  
  • The laboratories of Jason Held and Kerry Kornfeld at Washington University School of Medicine are jointly seeking a postdoctoral research associate to investigate redox biology in the model organism C. elegans as it relates to lifespan extension and stress-signaling responses. See the job posting for specific instructions on how to apply. No application deadline is provided.  
  • There are multiple positions for postdoctoral research fellows at the Oklahoma Medical Research Foundation (Oklahoma City). This includes a position in the lab of Holly Van Remmen to study the role of oxidative stress, mitochondrial function and neuroinflammation on neuromuscular degeneration in aging and neurodegenerative disease. The Functional and Chemical Genomics Program also has multiple postdoctoral openings, including opportunities to conduct research in several labs that investigate stress responses in model organisms. No application deadlines are provided.    
  • Procter and Gamble (Cincinnati, Ohio) is accepting applications for a life sciences Ph.D. internship. The research project focuses on the impact of oxidative stress on circadian rhythms in keratinocytes and the use of niacinamide as a protective agent. There are no details about eligibility or a timeline for the project. Consider reaching out to the company for more information. No application deadline is provided.     
  • The lab of Jiemei Wang in the Department of Pharmaceutical Sciences at Wayne State University is searching for a postdoctoral fellow (job posting No. 044056). The postdoc will characterize the molecular mechanisms of stress signaling (e.g., oxidative stress) regulated by G protein–coupled receptors in endothelial cells and within the context of vascular disorders. No application deadline is provided.   
  • The Department of Cell Biology and Physiology at the University of New Mexico School of Medicine is recruiting an assistant professor in cancer biology. Special areas of research interest include angiogenesis, oxidative stress, inflammation, cell metabolism or tumorigenesis. The incumbent also will teach graduate and medical-school courses. The priority application deadline is Jan. 31.  

Author’s note  

If you are in search for a last-minute gift for any science-y peeps, be sure to check out the holiday gift guide in the latest issue of ASBMB Today for some fun ideas. And, word has it, there’s going to be some gift giveaways over at the ASBMB Twitter account this month, so follow along for more info.