Special Symposia

Na, K-ATPase and Related Transport ATPases Structure, Mechanism, Cell Biology, Health and Disease

Na, K-ATPase and Related Transport ATPases: Structure, Mechanism, Cell Biology, Health and Disease

August 30-September 5, 2014
De Werelt Conference Centre
Lunteren, The Netherlands


Organizers photo
Jan Koenderink, Radboud Medical Center (The Netherlands)
Thomas Friedrich, Tech University of Berlin (Germany)

The triannual P-type ATPase Conference will be held in 2014 for the 14th time since 1973,  It has acquired an outstandingly prestigious reputation as an event, which is not to be missed for researchers in the field. In continuation of this tradition, the character of a highly specialized meeting will be kept, which at the same time will incorporate all aspects of the P-type transport ATPases by being open to a wide variety of experimental techniques that address questions ranging from the molecular level to the role of these enzymes in health and disease. Na+,K+-, H+,K+-, Ca2+-, Cu+-ATPases and their relatives have extremely important physiological roles as ion transporters. Some P-type ATPases are phospholipid transporters, and for many others substrate specificity has still to be assigned. Thus, these enzymes are much more than ion pumps, and also play complex roles in cell biology that were unimagined 10-15 years ago, which is underlined by their involvement in numerous human inherited diseases. In the last years, tremendous progress in understanding the function of P-type ATPases has been achieved by the elucidation of high resolution crystal structures, which have given way to novel approaches of scientific investigation. The exciting implications regarding bioinformatics and molecular modeling are only starting to emerge. Altogether, this interdisciplinary meeting brings together biochemical, biophysical, physiological, medical, genetics and cell biology investigators with a strong core of shared interests, and thus provides a platform for fruitful interactions and discussions amongst peers. Whereas the range of new discoveries is expanding rapidly, the sharp focus of the meeting to a well-specified class of enzymes ensures its persistent coherence.


Todd Graham, Department of Biological Sciences, Vanderbilt University, USA.
Jerry Lingrel, Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, USA.
Poul Nissen, Center for Membrane Pumps in Cells and Disease, University of Aarhus, Denmark.
Michael Palmgren, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.
Chikashi Toyoshima, Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan


The meeting addresses all researchers world-wide who are doing research in transport P-type ATPases and provides a platform for discussions amongst people from all stages of their academic careers.