Special Symposia

Membrane-Anchored Serine Proteases

SEPTEMBER 19–22, 2013 • William F. Bolger Center, Potomac, Md.


Toni Antalis, University of Maryland School of Medicine
Thomas Bugge, National Institute of Dental and Craniofacial Research, NIH


“The protease corin: from physiology to pathology”
Qingyu Wu, The Cleveland Clinic Lerner Research Institute


Researchers at academic institutions, government and industry who work on genomic,
biochemical, cell biological, physiological and pathophysiological
aspects of membrane-anchored serine proteases.



Membrane‐Anchored Serine Proteases as Guardians of Epithelial Integrity
Topics include barrier function, tissue remodeling, repair and regeneration.
Edith Hummler, University de Lausanne
Membrane‐Anchored Serine Proteases in Embryonic Development and Reproduction
Topics include fertilization, tissue morphogenesis, neural tube closure.
Eric Camerer, Paris Cardiovascular Research Centre & Université Paris-Descartes
Identification of Target Substrates for Membrane‐Anchored Serine Proteases: Genetic,Proteomic, and Biochemical Approaches
Topics will address targets including peptide hormones,growth factors, receptors, enzymes, adhesion molecules and viral coat proteins.
Charles Craik, University of California- San Francisco
Mingdon Huang, Beth Israel Deaconess Medical Center 

Regulation of Membrane‐Anchored Serine Proteases: synthesis, zymogen activation,inhibition, trafficking and beyond

Topics include Kunitz and serpin inhibitors, trafficking and membrane localization, ectodomain shedding, and zymogen activation.
Hiroaki Kataoka, University of Miyazaki 

Membrane‐Anchored Serine Proteases as Regulators of Homeostasis
Topics include hearing, hormonal regulation of blood pressure, ion and water transport and iron homeostasis.
Shaun Coughlin, Cardiovascular Research Institute- UCSF
Membrane‐Anchored Serine Proteases in Human Diseases
Topics include roles in cancer, inflammation, hypertension, viral infection.
Karin List, Wayne State University School of Medicine