Ali Shilatifard, Stowers Institute for Medical Research, Co-organizer


Raymond Trievel, University of Michigan,












Program Now Available!

The Eukaryotic RNA polymerase II and chromatin play a pivotal role in regulating gene expression. A central challenge to current research is to determine how RNA polymerase II coordinates the synthesis of messenger RNA, resulting in proper development and cellular regulation. Due to the expansion in the breadth and impact of both RNA polymerase II and chromatin in the regulation of gene expression, cellular development and the pathogenesis of human diseases, ASBMB has sponsored a small, focused meeting titled, Transcriptional Regulation by Chromatin and RNA polymerase II.  The 2012 ASBMB Symposium on Transcriptional Regulation by Chromatin and RNA Polymerase II represents the 5th anniversary of this meeting. Attendance at these symposia capped at about 200 participants and includes principal investigators, postdoctoral fellows, students, and scientists from pharmaceutical companies. 

The sessions will cover recent findings in transcriptional initiation, elongation and termination and the role of RNA polymerase II, its C-terminal domain and the associated factors in this process. The roles of chromatin and chromosomes, their interacting proteins and post-translational modifications, their numerous transcriptional properties and their role in development also will be addressed. Oral presentations at the symposia will be chosen from submitted abstracts, which is due by March 1st 2012. The applications accepted for poster presentations will compete for two $1,000 awards. 

The plenary lecture for this year’s symposium will be presented by Dr. Ramin Shiekhattar (Wistar Institute) who will describe his work on the functions of long non-coding RNAs in transcriptional regulation and during development and disease pathogenesis. Due to space limitations, we anticipate another oversubscription for this meeting. In this case, we will make a concerted effort to ensure that each research group wishing to participate is represented. The status of all submitted abstracts will be posted on the ASBMB Web site. We look forward to seeing you in Snowbird for an exciting and enlightening symposium!   

Meeting Program 





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